| Disease ID | Disease name | Source of annotation with XPC | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| 278700 | XERODERMA PIGMENTOSUM, COMPLEMENTATION GROUP A | ClinVar | link to OMIM | 2 | XPA, XPC |
| 278720 | XERODERMA PIGMENTOSUM, COMPLEMENTATION GROUP C | ClinVar, OMIM, HUMSAVAR | link to OMIM | 1 | XPC |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| Nucleotide excision repair | hsa03420 | 7.15 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Global Genomic NER (GG-NER) | R-HSA-109970 | 7.89 |
| SUMO E3 ligases SUMOylate target proteins | R-HSA-3108232 | 6.77 |
| DNA Damage Recognition in GG-NER | R-HSA-73940 | 11.98 |
| Metabolism of proteins | R-HSA-392499 | 3.41 |
| Formation of incision complex in GG-NER | R-HSA-73935 | 8.59 |
| Dual incision reaction in GG-NER | R-HSA-73941 | 8.59 |
| SUMOylation | R-HSA-2990846 | 6.68 |
| SUMOylation of DNA damage response and repair proteins | R-HSA-3108214 | 6.77 |
| DNA Repair | R-HSA-73894 | 5.8 |
| Post-translational protein modification | R-HSA-597592 | 4.54 |
| Nucleotide Excision Repair | R-HSA-73885 | 7.34 |
| GO term | GO ID | GO IC |
|---|---|---|
| structure-specific DNA binding | GO:0043566 | 4.98 |
| single-stranded DNA binding | GO:0003697 | 5.17 |
| nucleic acid binding | GO:0003676 | 1.44 |
| heteroduplex DNA loop binding | GO:0000404 | 9.05 |
| bubble DNA binding | GO:0000405 | 7.79 |
| DNA secondary structure binding | GO:0000217 | 6.6 |
| heterocyclic compound binding | GO:1901363 | 1.06 |
| mismatched DNA binding | GO:0030983 | 7.25 |
| binding | GO:0005488 | 0.18 |
| protein binding | GO:0005515 | 0.46 |
| DNA binding | GO:0003677 | 1.92 |
| DNA insertion or deletion binding | GO:0032135 | 7.95 |
| double-stranded DNA binding | GO:0003690 | 3.09 |
| organic cyclic compound binding | GO:0097159 | 1.05 |
| damaged DNA binding | GO:0003684 | 5.58 |