Gene table of YAP1 : Yes associated protein 1

Gene-disease associations table

Disease ID	Disease name	Source of annotation with YAP1	OMIM link	Number of associated genes	genes
120433	COLOBOMA, OCULAR, WITH OR WITHOUT HEARING IMPAIRMENT, CLEFT LIP/PALATE, AND/OR MENTAL RETARDATION	ClinVar, OMIM	link to OMIM	1	YAP1
120200	COLOBOMA, OCULAR, AUTOSOMAL DOMINANT	ClinVar	link to OMIM	4	GDF3, YAP1, FIBP, PAX6

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
Hippo signaling pathway	hsa04390	5.37

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
PPARA activates gene expression	R-HSA-1989781	6.18
Generic Transcription Pathway	R-HSA-212436	3.86
Gene Expression	R-HSA-74160	2.72
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)	R-HSA-400206	6.14
Signaling by Hippo	R-HSA-2028269	8.66
Metabolism	R-HSA-1430728	2.34
Signal Transduction	R-HSA-162582	1.78
YAP1- and WWTR1 (TAZ)-stimulated gene expression	R-HSA-2032785	8.12
Fatty acid, triacylglycerol, and ketone body metabolism	R-HSA-535734	5.44
Metabolism of lipids and lipoproteins	R-HSA-556833	3.79
Signaling by ERBB4	R-HSA-1236394	4.7
Nuclear signaling by ERBB4	R-HSA-1251985	7.7

Associated GO terms for Molecular function

GO term	GO ID	GO IC
protein C-terminus binding	GO:0008022	4.5
RNA polymerase II regulatory region DNA binding	GO:0001012	3.36
transcription factor activity, RNA polymerase II transcription factor binding	GO:0001076	4.84
macromolecular complex binding	GO:0044877	2.61
binding	GO:0005488	0.18
nucleic acid binding	GO:0003676	1.44
DNA binding	GO:0003677	1.92
heterocyclic compound binding	GO:1901363	1.06
sequence-specific DNA binding	GO:0043565	2.79
sequence-specific double-stranded DNA binding	GO:1990837	3.2
transcription corepressor activity	GO:0003714	4.33
transcription coactivator activity	GO:0003713	4.04
transcription cofactor activity	GO:0003712	3.44
transcription factor activity, transcription factor binding	GO:0000989	3.36
transcription factor activity, protein binding	GO:0000988	3.35
double-stranded DNA binding	GO:0003690	3.09
regulatory region nucleic acid binding	GO:0001067	3.03
proline-rich region binding	GO:0070064	6.79
core promoter binding	GO:0001047	4.71
core promoter sequence-specific DNA binding	GO:0001046	5.12
transcription regulatory region DNA binding	GO:0044212	3.03
RNA polymerase II core promoter sequence-specific DNA binding	GO:0000979	5.77
organic cyclic compound binding	GO:0097159	1.05
transcription regulatory region sequence-specific DNA binding	GO:0000976	3.24
RNA polymerase II regulatory region sequence-specific DNA binding	GO:0000977	3.37
protein binding	GO:0005515	0.46
regulatory region DNA binding	GO:0000975	3.03
chromatin binding	GO:0003682	3.64