Gene table of ZEB1 : zinc finger E-box binding homeobox 1

Gene-disease associations table

Disease IDDisease nameSource of annotation with ZEB1OMIM linkNumber of associated genesgenes
PS122000CORNEAL DYSTROPHY, POSTERIOR POLYMORPHOUSClinVar, OMIM link to OMIM 4OVOL2, ZEB1, VSX1, COL8A2
PS136800CORNEAL DYSTROPHY, FUCHS ENDOTHELIALClinVar, OMIM, HUMSAVAR link to OMIM 5SLC4A11, AGBL1, ZEB1, COL8A2, TCF4

Download the gene annotation in CSV format

Annotation of the gene ZEB1

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST

It is a TF of the genes:

It is regulated by the following TF:

Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
MicroRNAs in cancerhsa052065.38
Transcriptional misregulation in cancerhsa052025.21
Associated REACTOME pathways
Associated GO terms for Molecular function
GO termGO IDGO IC
macromolecular complex bindingGO:00448772.61
bindingGO:00054880.18
nucleic acid bindingGO:00036761.44
DNA bindingGO:00036771.92
E-box bindingGO:00708886.21
heterocyclic compound bindingGO:19013631.06
cation bindingGO:00431691.4
transition metal ion bindingGO:00469142.48
transcription corepressor activityGO:00037144.33
transcription coactivator activityGO:00037134.04
transcription cofactor activityGO:00037123.44
ion bindingGO:00431671.36
transcription factor activity, transcription factor bindingGO:00009893.36
transcription factor activity, protein bindingGO:00009883.35
metal ion bindingGO:00468721.41
RNA polymerase II transcription factor activity, sequence-specific DNA bindingGO:00009813.29
transcription factor bindingGO:00081343.46
regulatory region nucleic acid bindingGO:00010673.03
transcription regulatory region DNA bindingGO:00442123.03
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific bindingGO:00012274.61
transcription factor activity, sequence-specific DNA bindingGO:00037002.65
organic cyclic compound bindingGO:00971591.05
nucleic acid binding transcription factor activityGO:00010712.65
protein bindingGO:00055150.46
regulatory region DNA bindingGO:00009753.03
chromatin bindingGO:00036823.64
zinc ion bindingGO:00082702.66