Disease table of PERSISTENT MULLERIAN DUCT SYNDROME, TYPES I AND II OMIM ID: 261550

Gene-disease associations table

GeneAssociated with PERSISTENT MULLERIAN DUCT SYNDROME, TYPES I AND II inLink to HGNCCytogenetic bandNumber of associated diseasesAssociated diseases
AMHOMIM, HUMSAVARHGNC link19p13.31261550
AMHR2OMIM, HUMSAVARHGNC link12q13.131261550

Download the disease annotation in CSV format

Relations among genes:

Tandem repeat annotations from DGD
Cytogenetic band analysis
Transcription Factors (TF) annotation from TRRUST
regulated geneassociated to this disease# TFsTFs # TFs associated with this diseaseTFs associated with this disease
AMHYES10WT1, SF1, NR5A1, ESR1, SOX9, VDR, RELA, NR0B1, GATA4, NFKB10
AMHR2YES1APC0
Interactions from BIOGRID - physical
Interactions from BIOGRID - genetic
Interactions from STRING
Gene1Gene2Direct InteractionInteraction modeNumber of shared interactorsShared genes in interaction
AMHAMHR2Yesactivation, binding6FKBP1A, SMAD1, SMAD5, BMPR1B, SMAD9, ACVR1

Direct interactions graph
Interactions graph (direct and indirect interactions, when direct are not available)

Interactions from CORUM
Interactions from CENSUS
Interactions from PDB
Interactions from manually curated literature
Gene1Gene2Direct interactionMore information
AMHAMHR2maybeThey interact as ligand and receptor.
KEGG pathways annotation: shared terms / NET-GE enrichment

Shared terms

KEGG termKEGG term IDICNumber of genes with the same termGenes
TGF-beta signaling pathwayhsa043506.412AMH, AMHR2
Cytokine-cytokine receptor interactionhsa040604.672AMH, AMHR2

NET-GE enrichment

Term New enriched termICP valueGenes
TGF-beta signaling pathway (hsa04350) -6.410.001AMH, AMHR2
cAMP signaling pathway (hsa04024) NEW5.050.024AMH, AMHR2
Cytokine-cytokine receptor interaction (hsa04060) -4.670.012AMH, AMHR2
REACTOME pathways annotation: shared terms / NET-GE enrichment (no shared terms)
GO - molecular function annotation: shared terms / NET-GE enrichment

Shared terms

GOICNumber of genes with the same GOGenes
binding (GO:0005488) 0.182AMH, AMHR2
protein binding (GO:0005515) 0.462AMH, AMHR2

NET-GE enrichment

Term New enriched termICP valueGenes
growth factor activity (GO:0008083) NEW4.660.035AMH, AMHR2
hormone binding (GO:0042562) NEW5.530.004AMH, AMHR2
GO - biological process annotation: shared terms / NET-GE enrichment

Shared terms

GOICNumber of genes with the same GOGenes
developmental process (GO:0032502) 1.362AMH, AMHR2
sex differentiation (GO:0007548) 6.332AMH, AMHR2
single organism reproductive process (GO:0044702) 2.732AMH, AMHR2
reproductive structure development (GO:0048608) 4.082AMH, AMHR2
reproductive process (GO:0022414) 2.552AMH, AMHR2
cellular process (GO:0009987) 0.262AMH, AMHR2
gonad development (GO:0008406) 4.922AMH, AMHR2
anatomical structure regression (GO:0060033) 7.242AMH, AMHR2
regulation of cellular process (GO:0050794) 0.52AMH, AMHR2
single-organism developmental process (GO:0044767) 1.492AMH, AMHR2
developmental process involved in reproduction (GO:0003006) 3.362AMH, AMHR2
animal organ development (GO:0048513) 2.532AMH, AMHR2
biological regulation (GO:0065007) 0.392AMH, AMHR2
Mullerian duct regression (GO:0001880) 8.342AMH, AMHR2
negative regulation of biological process (GO:0048519) 1.332AMH, AMHR2
single-organism cellular process (GO:0044763) 0.652AMH, AMHR2
regulation of biological process (GO:0050789) 0.452AMH, AMHR2
single-organism process (GO:0044699) 0.482AMH, AMHR2
anatomical structure development (GO:0048856) 1.582AMH, AMHR2

NET-GE enrichment

Term New enriched termICP valueGenes
sex differentiation (GO:0007548) -6.330.001AMH, AMHR2
ovulation cycle process (GO:0022602) NEW5.250.017AMH, AMHR2
anatomical structure regression (GO:0060033) -7.240.0AMH, AMHR2
Mullerian duct regression (GO:0001880) -8.340.0AMH, AMHR2
GO - cellular component annotation: shared terms / NET-GE enrichment (no shared terms)