Disease table of WHITE SPONGE NEVUS OMIM ID: PS193900

Gene-disease associations table

GeneAssociated with WHITE SPONGE NEVUS inLink to HGNCCytogenetic bandNumber of associated diseasesAssociated diseases
KRT13ClinVar, OMIM, HUMSAVARHGNC link17q21.21PS193900
KRT4ClinVar, OMIM, HUMSAVARHGNC link12q13.131PS193900

Download the disease annotation in CSV format

Relations among genes:

Tandem repeat annotations from DGD
Cytogenetic band analysis
Transcription Factors (TF) annotation from TRRUST
regulated geneassociated to this disease# TFsTFs # TFs associated with this diseaseTFs associated with this disease
KRT13YES1NR1H40
KRT4YES1ELF30
Interactions from BIOGRID - physical
Gene1Gene2Direct InteractionNumber of shared interactorsShared genes in interaction
KRT13KRT4Yes2SHC1, CUL3

Direct interactions graph
Interactions graph (direct and indirect interactions, when direct are not available)

Interactions from BIOGRID - genetic
Interactions from STRING
Interactions from CORUM
Interactions from CENSUS
Interactions from PDB
Interactions from manually curated literature
Gene1Gene2Direct interactionMore information
KRT13KRT4yes, complexThey form a heterotetramer of two type I and two type II keratins. Keratin-13 is generally associated with keratin-4. [UniProt]
KEGG pathways annotation: shared terms / NET-GE enrichment (no shared terms)
REACTOME pathways annotation: shared terms / NET-GE enrichment (no shared terms)
GO - molecular function annotation: shared terms / NET-GE enrichment

Shared terms

GOICNumber of genes with the same GOGenes
binding (GO:0005488) 0.182KRT13, KRT4
protein binding (GO:0005515) 0.462KRT13, KRT4
structural molecule activity (GO:0005198) 3.12KRT13, KRT4

NET-GE enrichment

Term New enriched termICP valueGenes
structural molecule activity (GO:0005198) -3.10.006KRT13, KRT4
GO - biological process annotation: shared terms / NET-GE enrichment

Shared terms

GOICNumber of genes with the same GOGenes
organelle organization (GO:0006996) 2.022KRT13, KRT4
cytoskeleton organization (GO:0007010) 3.222KRT13, KRT4
cellular process (GO:0009987) 0.262KRT13, KRT4
cellular component organization (GO:0016043) 1.242KRT13, KRT4
cellular component organization or biogenesis (GO:0071840) 1.222KRT13, KRT4
single-organism process (GO:0044699) 0.482KRT13, KRT4

NET-GE enrichment

Term New enriched termICP valueGenes
cytoskeleton organization (GO:0007010) -3.220.048KRT13, KRT4
GO - cellular component annotation: shared terms / NET-GE enrichment

Shared terms

GOICNumber of genes with the same GOGenes
cytoskeleton (GO:0005856) 2.552KRT13, KRT4
intermediate filament cytoskeleton (GO:0045111) 5.792KRT13, KRT4
supramolecular fiber (GO:0099512) 3.312KRT13, KRT4
polymeric cytoskeletal fiber (GO:0099513) 3.312KRT13, KRT4
intracellular non-membrane-bounded organelle (GO:0043232) 1.762KRT13, KRT4
nucleus (GO:0005634) 1.072KRT13, KRT4
keratin filament (GO:0045095) 5.212KRT13, KRT4
cell part (GO:0044464) 0.112KRT13, KRT4
organelle part (GO:0044422) 0.792KRT13, KRT4
intracellular organelle part (GO:0044446) 0.812KRT13, KRT4
intracellular organelle (GO:0043229) 0.512KRT13, KRT4
non-membrane-bounded organelle (GO:0043228) 1.762KRT13, KRT4
cytoskeletal part (GO:0044430) 2.492KRT13, KRT4
intracellular part (GO:0044424) 0.282KRT13, KRT4
membrane-bounded organelle (GO:0043227) 0.472KRT13, KRT4
organelle (GO:0043226) 0.42KRT13, KRT4
intermediate filament (GO:0005882) 4.482KRT13, KRT4
intracellular membrane-bounded organelle (GO:0043231) 0.62KRT13, KRT4

NET-GE enrichment

Term New enriched termICP valueGenes
cytoskeleton (GO:0005856) -2.550.04KRT13, KRT4
intermediate filament cytoskeleton (GO:0045111) -5.790.0KRT13, KRT4
keratin filament (GO:0045095) -5.210.001KRT13, KRT4
intermediate filament (GO:0005882) -4.480.003KRT13, KRT4