Gene table of CCL3 : C-C motif chemokine ligand 3

Gene-disease associations table

Disease ID	Disease name	Source of annotation with CCL3	OMIM link	Number of associated genes	genes
609423	HUMAN IMMUNODEFICIENCY VIRUS TYPE 1, SUSCEPTIBILITY TO	OMIM	link to OMIM	16	HLA-C, IFNG, CCL3, CD209, IL4R, KIR3DL1, CCL2, TLR3, CCR2, CX3CR1, CCL11, CCR5, CXCL12, CCL3L1, CXCR1, IL10

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
Salmonella infection	hsa05132	6.29
Rheumatoid arthritis	hsa05323	6.05
Toll-like receptor signaling pathway	hsa04620	6.0
Chagas disease (American trypanosomiasis)	hsa05142	5.99
Chemokine signaling pathway	hsa04062	5.19
Cytokine-cytokine receptor interaction	hsa04060	4.67

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
Signaling by GPCR	R-HSA-372790	2.68
Class A/1 (Rhodopsin-like receptors)	R-HSA-373076	4.69
Peptide ligand-binding receptors	R-HSA-375276	5.41
Chemokine receptors bind chemokines	R-HSA-380108	7.2
GPCR ligand binding	R-HSA-500792	4.19
Signal Transduction	R-HSA-162582	1.78

Associated GO terms for Molecular function

GO term	GO ID	GO IC
cytokine receptor binding	GO:0005126	4.14
chemoattractant activity	GO:0042056	6.48
cytokine activity	GO:0005125	4.34
chemokine activity	GO:0008009	5.87
calcium-dependent protein kinase C activity	GO:0004698	8.35
CCR5 chemokine receptor binding	GO:0031730	7.95
binding	GO:0005488	0.18
G-protein coupled receptor binding	GO:0001664	4.18
molecular function regulator	GO:0098772	2.51
CCR chemokine receptor binding	GO:0048020	6.21
lipase activator activity	GO:0060229	7.1
chemokine receptor binding	GO:0042379	5.7
protein kinase C activity	GO:0004697	6.97
protein serine/threonine kinase activity	GO:0004674	3.64
transferase activity	GO:0016740	1.95
phospholipase activator activity	GO:0016004	7.25
protein kinase activity	GO:0004672	3.27
identical protein binding	GO:0042802	2.63
enzyme regulator activity	GO:0030234	2.85
kinase activity	GO:0016301	2.93
CCR1 chemokine receptor binding	GO:0031726	7.95
catalytic activity	GO:0003824	1.05
calcium-dependent protein kinase activity	GO:0010857	7.25
phosphotransferase activity, alcohol group as acceptor	GO:0016773	3.08
transferase activity, transferring phosphorus-containing groups	GO:0016772	2.77
calcium-dependent protein serine/threonine kinase activity	GO:0009931	7.34
protein binding	GO:0005515	0.46
receptor binding	GO:0005102	2.43
enzyme activator activity	GO:0008047	3.56