Gene table of CCR2 : C-C motif chemokine receptor 2

Gene-disease associations table

Disease ID	Disease name	Source of annotation with CCR2	OMIM link	Number of associated genes	genes
609423	HUMAN IMMUNODEFICIENCY VIRUS TYPE 1, SUSCEPTIBILITY TO	ClinVar, OMIM	link to OMIM	16	HLA-C, IFNG, CCL3, CD209, IL4R, KIR3DL1, CCL2, TLR3, CCR2, CX3CR1, CCL11, CCR5, CXCL12, CCL3L1, CXCR1, IL10

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
Chemokine signaling pathway	hsa04062	5.19
Cytokine-cytokine receptor interaction	hsa04060	4.67

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
Defensins	R-HSA-1461973	7.49
Beta defensins	R-HSA-1461957	7.81
Signaling by GPCR	R-HSA-372790	2.68
G alpha (i) signalling events	R-HSA-418594	5.1
Class A/1 (Rhodopsin-like receptors)	R-HSA-373076	4.69
Immune System	R-HSA-168256	2.37
Peptide ligand-binding receptors	R-HSA-375276	5.41
Innate Immune System	R-HSA-168249	3.17
Chemokine receptors bind chemokines	R-HSA-380108	7.2
GPCR downstream signaling	R-HSA-388396	3.07
GPCR ligand binding	R-HSA-500792	4.19
Signal Transduction	R-HSA-162582	1.78

Associated GO terms for Molecular function

GO term	GO ID	GO IC
cytokine receptor binding	GO:0005126	4.14
signaling receptor activity	GO:0038023	2.49
chemokine binding	GO:0019956	6.69
C-C chemokine binding	GO:0019957	7.79
cytokine binding	GO:0019955	5.21
enzyme binding	GO:0019899	2.27
chemokine receptor activity	GO:0004950	6.52
molecular transducer activity	GO:0060089	2.32
binding	GO:0005488	0.18
signal transducer activity	GO:0004871	2.28
G-protein coupled receptor binding	GO:0001664	4.18
CCR chemokine receptor binding	GO:0048020	6.21
C-C chemokine receptor activity	GO:0016493	7.25
G-protein coupled peptide receptor activity	GO:0008528	4.86
G-protein coupled receptor activity	GO:0004930	2.95
chemokine receptor binding	GO:0042379	5.7
identical protein binding	GO:0042802	2.63
protein homodimerization activity	GO:0042803	3.16
CCR2 chemokine receptor binding	GO:0031727	8.64
protein kinase binding	GO:0019901	3.44
kinase binding	GO:0019900	3.32
peptide receptor activity	GO:0001653	4.84
receptor binding	GO:0005102	2.43
chemokine (C-C motif) ligand 5 binding	GO:0071791	8.64
G-protein coupled chemoattractant receptor activity	GO:0001637	6.52
transmembrane signaling receptor activity	GO:0004888	2.57
protein binding	GO:0005515	0.46
protein dimerization activity	GO:0046983	2.72
cytokine receptor activity	GO:0004896	5.24
transmembrane receptor activity	GO:0099600	2.53
receptor activity	GO:0004872	2.32