Gene table of CD40 : CD40 molecule

Gene-disease associations table

Disease IDDisease nameSource of annotation with CD40OMIM linkNumber of associated genesgenes
PS308230IMMUNODEFICIENCY WITH HYPER-IGMClinVar, OMIM, HUMSAVAR link to OMIM 4AICDA, CD40LG, UNG, CD40

Download the gene annotation in CSV format

Annotation of the gene CD40

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST

It is regulated by the following TF:

Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Cytokine-cytokine receptor interactionhsa040604.67
Systemic lupus erythematosushsa053225.95
Autoimmune thyroid diseasehsa053206.62
Asthmahsa053107.34
Toll-like receptor signaling pathwayhsa046206.0
Allograft rejectionhsa053306.91
Transcriptional misregulation in cancerhsa052025.21
Intestinal immune network for IgA productionhsa046726.79
Cell adhesion molecules (CAMs)hsa045145.36
Epstein-Barr virus infectionhsa051694.97
Malariahsa051447.15
Toxoplasmosishsa051455.71
Primary immunodeficiencyhsa053407.52
NF-kappa B signaling pathwayhsa040646.21
HTLV-I infectionhsa051664.59
Viral myocarditishsa054166.45
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
TNFR2 non-canonical NF-kB pathwayR-HSA-56685416.4
Immune SystemR-HSA-1682562.37
Cytokine Signaling in Immune systemR-HSA-12802153.74
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathwayR-HSA-56765948.89
Adaptive Immune SystemR-HSA-12802183.19
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cellR-HSA-1989334.7
Associated GO terms for Molecular function
GO termGO IDGO IC
antigen bindingGO:00038235.02
ubiquitin protein ligase bindingGO:00316254.17
ubiquitin-like protein ligase bindingGO:00443894.15
protein bindingGO:00055150.46
molecular transducer activityGO:00600892.32
enzyme bindingGO:00198992.27
death receptor activityGO:00050356.56
transmembrane signaling receptor activityGO:00048882.57
bindingGO:00054880.18
signal transducer activityGO:00048712.28
receptor activityGO:00048722.32
signaling receptor activityGO:00380232.49
transmembrane receptor activityGO:00996002.53
tumor necrosis factor-activated receptor activityGO:00050316.56