| Disease ID | Disease name | Source of annotation with CD81 | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| PS607594 | IMMUNODEFICIENCY, COMMON VARIABLE | OMIM | link to OMIM | 12 | NFKB1, CD19, IL21, CR2, MS4A1, LRBA, NFKB2, CD81, IKZF1, TNFRSF13C, TNFRSF13B, ICOS |
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| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| B cell receptor signaling pathway | hsa04662 | 6.52 |
| Hepatitis C | hsa05160 | 5.68 |
| Malaria | hsa05144 | 7.15 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Immune System | R-HSA-168256 | 2.37 |
| Adaptive Immune System | R-HSA-1280218 | 3.19 |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | R-HSA-198933 | 4.7 |
| GO term | GO ID | GO IC |
|---|---|---|
| antigen binding | GO:0003823 | 5.02 |
| transferrin receptor binding | GO:1990459 | 7.66 |
| MHC protein complex binding | GO:0023023 | 6.79 |
| macromolecular complex binding | GO:0044877 | 2.61 |
| binding | GO:0005488 | 0.18 |
| protein binding | GO:0005515 | 0.46 |
| protein complex binding | GO:0032403 | 3.09 |
| receptor binding | GO:0005102 | 2.43 |
| MHC class II protein complex binding | GO:0023026 | 6.97 |