| Disease ID | Disease name | Source of annotation with CHRM3 | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| 100100 | PRUNE BELLY SYNDROME | OMIM | link to OMIM | 1 | CHRM3 |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| Salivary secretion | hsa04970 | 6.23 |
| Gastric acid secretion | hsa04971 | 6.48 |
| Pancreatic secretion | hsa04972 | 6.07 |
| Calcium signaling pathway | hsa04020 | 5.22 |
| Insulin secretion | hsa04911 | 6.18 |
| Cholinergic synapse | hsa04725 | 5.88 |
| Neuroactive ligand-receptor interaction | hsa04080 | 4.58 |
| Regulation of actin cytoskeleton | hsa04810 | 4.9 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Regulation of insulin secretion | R-HSA-422356 | 6.66 |
| Amine ligand-binding receptors | R-HSA-375280 | 7.59 |
| Signaling by GPCR | R-HSA-372790 | 2.68 |
| GPCR downstream signaling | R-HSA-388396 | 3.07 |
| Class A/1 (Rhodopsin-like receptors) | R-HSA-373076 | 4.69 |
| Gastrin-CREB signalling pathway via PKC and MAPK | R-HSA-881907 | 4.26 |
| Acetylcholine regulates insulin secretion | R-HSA-399997 | 9.66 |
| Integration of energy metabolism | R-HSA-163685 | 6.24 |
| G alpha (q) signalling events | R-HSA-416476 | 5.42 |
| Metabolism | R-HSA-1430728 | 2.34 |
| Muscarinic acetylcholine receptors | R-HSA-390648 | 10.66 |
| GPCR ligand binding | R-HSA-500792 | 4.19 |
| Signal Transduction | R-HSA-162582 | 1.78 |
| GO term | GO ID | GO IC |
|---|---|---|
| signaling receptor activity | GO:0038023 | 2.49 |
| acetylcholine receptor activity | GO:0015464 | 6.3 |
| drug binding | GO:0008144 | 5.03 |
| phosphoric ester hydrolase activity | GO:0042578 | 3.82 |
| molecular transducer activity | GO:0060089 | 2.32 |
| binding | GO:0005488 | 0.18 |
| signal transducer activity | GO:0004871 | 2.28 |
| cation binding | GO:0043169 | 1.4 |
| G-protein coupled receptor activity | GO:0004930 | 2.95 |
| phosphoric diester hydrolase activity | GO:0008081 | 5.23 |
| ion binding | GO:0043167 | 1.36 |
| G-protein coupled neurotransmitter receptor activity | GO:0099528 | 7.79 |
| hydrolase activity | GO:0016787 | 1.9 |
| neurotransmitter receptor activity | GO:0030594 | 5.5 |
| acetylcholine binding | GO:0042166 | 6.56 |
| neurotransmitter binding | GO:0042165 | 6.34 |
| catalytic activity | GO:0003824 | 1.05 |
| hydrolase activity, acting on ester bonds | GO:0016788 | 3.1 |
| G-protein coupled acetylcholine receptor activity | GO:0016907 | 7.79 |
| G-protein coupled amine receptor activity | GO:0008227 | 5.83 |
| phosphatidylinositol phospholipase C activity | GO:0004435 | 6.41 |
| ammonium ion binding | GO:0070405 | 5.81 |
| transmembrane signaling receptor activity | GO:0004888 | 2.57 |
| phospholipase C activity | GO:0004629 | 6.3 |
| protein binding | GO:0005515 | 0.46 |
| phospholipase activity | GO:0004620 | 5.16 |
| lipase activity | GO:0016298 | 4.96 |
| transmembrane receptor activity | GO:0099600 | 2.53 |
| receptor activity | GO:0004872 | 2.32 |