Gene table of DCC : DCC netrin 1 receptor

Gene-disease associations table

Disease IDDisease nameSource of annotation with DCCOMIM linkNumber of associated genesgenes
133239ESOPHAGEAL CANCEROMIM link to OMIM 7TGFBR2, DCC, DLEC1, RNF6, DEC1, WWOX, LZTS1
114500COLORECTAL CANCEROMIM link to OMIM 30TLR4, RAD54B, PTPRJ, TP53, EP300, PTPN12, ODC1, FLCN, TLR2, BAX, PLA2G2A, AURKA, NRAS, APC, MCC, TRIM28, MLH3, AKT1, MT-CO1, AXIN2, CTNNB1, PDGFRL, PIK3CA, KAT5, DCC, BRAF, CCND1, FGFR3, DLC1, BUB1B
PS157600MIRROR MOVEMENTSClinVar, OMIM link to OMIM 3RAD51, DCC, DNAL4

Download the gene annotation in CSV format

Annotation of the gene DCC

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST

It is regulated by the following TF:

Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Axon guidancehsa043605.63
Colorectal cancerhsa052106.52
Pathways in cancerhsa052003.98
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
DSCAM interactionsR-HSA-3761729.52
Netrin mediated repulsion signalsR-HSA-4188869.66
DCC mediated attractive signalingR-HSA-4188859.18
Role of second messengers in netrin-1 signalingR-HSA-4188909.66
Caspase activation via extrinsic apoptotic signalig pathwayR-HSA-53577698.34
Ligand-independent caspase activation via DCCR-HSA-4188899.66
Cell-Cell communicationR-HSA-15009315.87
Programmed Cell DeathR-HSA-53578015.65
ApoptosisR-HSA-1095815.68
Axon guidanceR-HSA-4224753.93
Developmental BiologyR-HSA-12667383.48
Netrin-1 signalingR-HSA-3737527.59
Associated GO terms for Molecular function
GO termGO IDGO IC
signaling receptor activityGO:00380232.49
signal transducer activityGO:00048712.28
netrin receptor activityGO:00050429.05
molecular transducer activityGO:00600892.32
transmembrane signaling receptor activityGO:00048882.57
receptor activityGO:00048722.32
protein bindingGO:00055150.46
transmembrane receptor activityGO:00996002.53
bindingGO:00054880.18