Gene table of F8 : coagulation factor VIII

Gene-disease associations table

Disease IDDisease nameSource of annotation with F8OMIM linkNumber of associated genesgenes
306700HEMOPHILIA AClinVar, OMIM, HUMSAVAR link to OMIM 1F8
134500FACTOR VIII DEFICIENCYClinVar link to OMIM 1F8

Download the gene annotation in CSV format

Annotation of the gene F8

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST

It is regulated by the following TF:

Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Complement and coagulation cascadeshsa046106.58
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
Platelet degranulation R-HSA-1146086.68
Platelet activation, signaling and aggregationR-HSA-760025.15
Response to elevated platelet cytosolic Ca2+R-HSA-760056.59
Intrinsic Pathway of Fibrin Clot FormationR-HSA-1408378.52
Common Pathway of Fibrin Clot FormationR-HSA-1408758.52
Formation of Fibrin Clot (Clotting Cascade)R-HSA-1408777.7
HemostasisR-HSA-1095823.98
Associated GO terms for Molecular function
GO termGO IDGO IC
cation bindingGO:00431691.4
metal ion bindingGO:00468721.41
transition metal ion bindingGO:00469142.48
ion bindingGO:00431671.36
catalytic activityGO:00038241.05
bindingGO:00054880.18
protein bindingGO:00055150.46
copper ion bindingGO:00055075.71
oxidoreductase activityGO:00164913.12