Gene table of FASLG : Fas ligand

Gene-disease associations table

Disease ID	Disease name	Source of annotation with FASLG	OMIM link	Number of associated genes	genes
601859	AUTOIMMUNE LYMPHOPROLIFERATIVE SYNDROME	ClinVar, OMIM, HUMSAVAR	link to OMIM	2	FASLG, FAS
211980	LUNG CANCER	OMIM	link to OMIM	17	RASSF1, PARK2, IRF1, CASP8, ERBB2, PPP2R1B, FASLG, MAP3K8, PIK3CA, BRAF, KRAS, DLEC1, SLC22A18, ERCC6, CYP2A6, MXRA5, EGFR

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
Proteoglycans in cancer	hsa05205	5.02
Natural killer cell mediated cytotoxicity	hsa04650	5.53
Autoimmune thyroid disease	hsa05320	6.62
MAPK signaling pathway	hsa04010	4.63
Non-alcoholic fatty liver disease (NAFLD)	hsa04932	5.51
Allograft rejection	hsa05330	6.91
Graft-versus-host disease	hsa05332	6.84
Chagas disease (American trypanosomiasis)	hsa05142	5.99
African trypanosomiasis	hsa05143	7.68
Ras signaling pathway	hsa04014	4.9
Neurotrophin signaling pathway	hsa04722	5.78
Herpes simplex infection	hsa05168	5.08
Measles	hsa05162	5.6
FoxO signaling pathway	hsa04068	5.63
Apoptosis	hsa04210	6.23
Influenza A	hsa05164	5.21
Type I diabetes mellitus	hsa04940	6.79
Pathways in cancer	hsa05200	3.98
Hepatitis B	hsa05161	5.52
Cytokine-cytokine receptor interaction	hsa04060	4.67
PI3K-Akt signaling pathway	hsa04151	4.21

Associated REACTOME pathways

Associated GO terms for Molecular function

GO term	GO ID	GO IC
cytokine receptor binding	GO:0005126	4.14
tumor necrosis factor receptor superfamily binding	GO:0032813	5.89
death receptor binding	GO:0005123	6.91
tumor necrosis factor receptor binding	GO:0005164	6.3
cytokine activity	GO:0005125	4.34
binding	GO:0005488	0.18
protein binding	GO:0005515	0.46
receptor binding	GO:0005102	2.43