Gene table of GLUD1 : glutamate dehydrogenase 1

Gene-disease associations table

Disease ID	Disease name	Source of annotation with GLUD1	OMIM link	Number of associated genes	genes
PS256450	HYPERINSULINEMIA HYPOGLYCEMIA	ClinVar, OMIM, HUMSAVAR	link to OMIM	7	GCK, INSR, SLC16A1, GLUD1, HADH, ABCC8, KCNJ11

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Annotation of the gene GLUD1

Associated genes in ENSEMBL

ENSG00000148672

Associated proteins - SwissProt Accession ID

P00367

Associated PDB IDs

Cytogenetic Band

10q23.2

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
Arginine and proline metabolism	hsa00330	6.84
Proximal tubule bicarbonate reclamation	hsa04964	8.24
Metabolic pathways	hsa01100	2.49
Alanine, aspartate and glutamate metabolism	hsa00250	7.64
Nitrogen metabolism	hsa00910	8.6
D-Glutamine and D-glutamate metabolism	hsa00471	10.77

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
Metabolism of amino acids and derivatives	R-HSA-71291	5.4
Metabolism	R-HSA-1430728	2.34
Amino acid synthesis and interconversion (transamination)	R-HSA-70614	8.89

Associated GO terms for Molecular function

GO term	GO ID	GO IC
purine ribonucleoside triphosphate binding	GO:0035639	2.22
NAD binding	GO:0051287	5.77
protein binding	GO:0005515	0.46
binding	GO:0005488	0.18
ion binding	GO:0043167	1.36
amino acid binding	GO:0016597	5.71
heterocyclic compound binding	GO:1901363	1.06
nucleoside phosphate binding	GO:1901265	1.96
oxidoreductase activity	GO:0016491	3.12
anion binding	GO:0043168	4.17
coenzyme binding	GO:0050662	4.53
leucine binding	GO:0070728	7.95
nucleotide binding	GO:0000166	1.96
guanyl ribonucleotide binding	GO:0032561	3.73
purine nucleoside binding	GO:0001883	2.22
ribonucleoside binding	GO:0032549	2.22
purine nucleotide binding	GO:0017076	2.19
nucleoside binding	GO:0001882	2.21
identical protein binding	GO:0042802	2.63
GTP binding	GO:0005525	3.78
carboxylic acid binding	GO:0031406	4.64
small molecule binding	GO:0036094	1.89
catalytic activity	GO:0003824	1.05
cofactor binding	GO:0048037	4.16
ADP binding	GO:0043531	6.24
oxidoreductase activity, acting on the CH-NH2 group of donors	GO:0016638	6.74
adenyl nucleotide binding	GO:0030554	2.4
carbohydrate derivative binding	GO:0097367	2.03
organic cyclic compound binding	GO:0097159	1.05
oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor	GO:0016639	9.05
glutamate dehydrogenase (NAD+) activity	GO:0004352	9.05
glutamate dehydrogenase [NAD(P)+] activity	GO:0004353	9.05
guanyl nucleotide binding	GO:0019001	3.73
adenyl ribonucleotide binding	GO:0032559	2.41
ATP binding	GO:0005524	2.43
NAD+ binding	GO:0070403	7.17
purine ribonucleotide binding	GO:0032555	2.2
purine ribonucleoside binding	GO:0032550	2.22
ribonucleotide binding	GO:0032553	2.19