| Disease ID | Disease name | Source of annotation with HLA-A | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| 608579 | SEVERE CUTANEOUS ADVERSE REACTION, SUSCEPTIBILITY TO | OMIM | link to OMIM | 2 | HLA-B, HLA-A |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| Antigen processing and presentation | hsa04612 | 6.04 |
| Natural killer cell mediated cytotoxicity | hsa04650 | 5.53 |
| Autoimmune thyroid disease | hsa05320 | 6.62 |
| Allograft rejection | hsa05330 | 6.91 |
| Viral carcinogenesis | hsa05203 | 5.08 |
| Graft-versus-host disease | hsa05332 | 6.84 |
| Cell adhesion molecules (CAMs) | hsa04514 | 5.36 |
| Phagosome | hsa04145 | 5.27 |
| Endocytosis | hsa04144 | 4.92 |
| Type I diabetes mellitus | hsa04940 | 6.79 |
| HTLV-I infection | hsa05166 | 4.59 |
| Epstein-Barr virus infection | hsa05169 | 4.97 |
| Viral myocarditis | hsa05416 | 6.45 |
| Herpes simplex infection | hsa05168 | 5.08 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Infectious disease | R-HSA-5663205 | 4.47 |
| Host Interactions of HIV factors | R-HSA-162909 | 5.99 |
| Immune System | R-HSA-168256 | 2.37 |
| Interferon alpha/beta signaling | R-HSA-909733 | 6.04 |
| Antigen processing-Cross presentation | R-HSA-1236975 | 5.88 |
| ER-Phagosome pathway | R-HSA-1236974 | 6.08 |
| Endosomal/Vacuolar pathway | R-HSA-1236977 | 6.92 |
| Cytokine Signaling in Immune system | R-HSA-1280215 | 3.74 |
| Antigen Presentation: Folding, assembly and peptide loading of class I MHC | R-HSA-983170 | 6.64 |
| Class I MHC mediated antigen processing & presentation | R-HSA-983169 | 4.65 |
| Interferon gamma signaling | R-HSA-877300 | 5.67 |
| HIV Infection | R-HSA-162906 | 5.22 |
| The role of Nef in HIV-1 replication and disease pathogenesis | R-HSA-164952 | 8.18 |
| Interferon Signaling | R-HSA-913531 | 4.95 |
| Nef mediated downregulation of MHC class I complex cell surface expression | R-HSA-164940 | 9.66 |
| Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters | R-HSA-164938 | 8.59 |
| Adaptive Immune System | R-HSA-1280218 | 3.19 |
| Disease | R-HSA-1643685 | 3.33 |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | R-HSA-198933 | 4.7 |
| GO term | GO ID | GO IC |
|---|---|---|
| antigen binding | GO:0003823 | 5.02 |
| beta-2-microglobulin binding | GO:0030881 | 7.34 |
| protein binding | GO:0005515 | 0.46 |
| peptide antigen binding | GO:0042605 | 6.18 |
| amide binding | GO:0033218 | 4.14 |
| T cell receptor binding | GO:0042608 | 7.95 |
| poly(A) RNA binding | GO:0044822 | 2.69 |
| macromolecular complex binding | GO:0044877 | 2.61 |
| binding | GO:0005488 | 0.18 |
| nucleic acid binding | GO:0003676 | 1.44 |
| TAP binding | GO:0046977 | 7.79 |
| protein complex binding | GO:0032403 | 3.09 |
| peptide binding | GO:0042277 | 4.22 |
| receptor binding | GO:0005102 | 2.43 |
| organic cyclic compound binding | GO:0097159 | 1.05 |
| heterocyclic compound binding | GO:1901363 | 1.06 |
| RNA binding | GO:0003723 | 2.36 |