Gene table of HMOX1 : heme oxygenase 1

Gene-disease associations table

Disease ID	Disease name	Source of annotation with HMOX1	OMIM link	Number of associated genes	genes
614034	HEME OXYGENASE 1 DEFICIENCY	OMIM	link to OMIM	1	HMOX1
606963	PULMONARY DISEASE, CHRONIC OBSTRUCTIVE	OMIM	link to OMIM	3	SERPINA1, HMOX1, MMP1

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
HIF-1 signaling pathway	hsa04066	5.9
Mineral absorption	hsa04978	7.09
Porphyrin and chlorophyll metabolism	hsa00860	7.41
MicroRNAs in cancer	hsa05206	5.38

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
Heme degradation	R-HSA-189483	10.4
Metabolism	R-HSA-1430728	2.34
Iron uptake and transport	R-HSA-917937	7.56
Transmembrane transport of small molecules	R-HSA-382551	3.79
Metabolism of porphyrins	R-HSA-189445	8.89

Associated GO terms for Molecular function

GO term	GO ID	GO IC
heme oxygenase (decyclizing) activity	GO:0004392	9.05
enzyme binding	GO:0019899	2.27
phosphoric ester hydrolase activity	GO:0042578	3.82
binding	GO:0005488	0.18
signal transducer activity	GO:0004871	2.28
heterocyclic compound binding	GO:1901363	1.06
oxidoreductase activity	GO:0016491	3.12
cation binding	GO:0043169	1.4
phosphoric diester hydrolase activity	GO:0008081	5.23
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	GO:0016705	4.65
ion binding	GO:0043167	1.36
phospholipase D activity	GO:0004630	7.79
metal ion binding	GO:0046872	1.41
identical protein binding	GO:0042802	2.63
protein homodimerization activity	GO:0042803	3.16
hydrolase activity	GO:0016787	1.9
heme binding	GO:0020037	4.86
hydrolase activity, acting on ester bonds	GO:0016788	3.1
catalytic activity	GO:0003824	1.05
phospholipase activity	GO:0004620	5.16
tetrapyrrole binding	GO:0046906	4.8
organic cyclic compound binding	GO:0097159	1.05
protein binding	GO:0005515	0.46
protein dimerization activity	GO:0046983	2.72
lipase activity	GO:0016298	4.96