Gene table of HSD11B2 : hydroxysteroid 11-beta dehydrogenase 2

Gene-disease associations table

Disease ID	Disease name	Source of annotation with HSD11B2	OMIM link	Number of associated genes	genes
218030	APPARENT MINERALOCORTICOID EXCESS	ClinVar, OMIM, HUMSAVAR	link to OMIM	1	HSD11B2

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
Aldosterone-regulated sodium reabsorption	hsa04960	7.41
Steroid hormone biosynthesis	hsa00140	6.93

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
Metabolism of lipids and lipoproteins	R-HSA-556833	3.79
Glucocorticoid biosynthesis	R-HSA-194002	9.81
Metabolism	R-HSA-1430728	2.34
Metabolism of steroid hormones and vitamin D	R-HSA-196071	7.89

Associated GO terms for Molecular function

GO term	GO ID	GO IC
steroid dehydrogenase activity	GO:0016229	6.34
coenzyme binding	GO:0050662	4.53
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	GO:0033764	6.48
oxidoreductase activity, acting on CH-OH group of donors	GO:0016614	4.83
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	GO:0016616	5.0
organic cyclic compound binding	GO:0097159	1.05
lipid binding	GO:0008289	3.26
nucleotide binding	GO:0000166	1.96
small molecule binding	GO:0036094	1.89
catalytic activity	GO:0003824	1.05
cofactor binding	GO:0048037	4.16
binding	GO:0005488	0.18
11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity	GO:0003845	9.05
NAD binding	GO:0051287	5.77
steroid binding	GO:0005496	5.24
heterocyclic compound binding	GO:1901363	1.06
nucleoside phosphate binding	GO:1901265	1.96
oxidoreductase activity	GO:0016491	3.12