| Disease ID | Disease name | Source of annotation with ITGB2 | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| 116920 | LEUKOCYTE ADHESION DEFICIENCY, TYPE I | ClinVar, OMIM, HUMSAVAR | link to OMIM | 1 | ITGB2 |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| Pertussis | hsa05133 | 6.46 |
| Phagosome | hsa04145 | 5.27 |
| Legionellosis | hsa05134 | 6.88 |
| Rheumatoid arthritis | hsa05323 | 6.05 |
| Tuberculosis | hsa05152 | 5.17 |
| Rap1 signaling pathway | hsa04015 | 4.97 |
| Cell adhesion molecules (CAMs) | hsa04514 | 5.36 |
| Leishmaniasis | hsa05140 | 6.32 |
| Leukocyte transendothelial migration | hsa04670 | 5.74 |
| Amoebiasis | hsa05146 | 5.82 |
| Staphylococcus aureus infection | hsa05150 | 6.64 |
| Malaria | hsa05144 | 7.15 |
| Natural killer cell mediated cytotoxicity | hsa04650 | 5.53 |
| Hippo signaling pathway | hsa04390 | 5.37 |
| HTLV-I infection | hsa05166 | 4.59 |
| Viral myocarditis | hsa05416 | 6.45 |
| Regulation of actin cytoskeleton | hsa04810 | 4.9 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Integrin cell surface interactions | R-HSA-216083 | 6.57 |
| Toll Like Receptor 4 (TLR4) Cascade | R-HSA-166016 | 6.11 |
| Immune System | R-HSA-168256 | 2.37 |
| Cell surface interactions at the vascular wall | R-HSA-202733 | 6.32 |
| Toll-Like Receptors Cascades | R-HSA-168898 | 5.91 |
| Extracellular matrix organization | R-HSA-1474244 | 4.91 |
| Innate Immune System | R-HSA-168249 | 3.17 |
| Adaptive Immune System | R-HSA-1280218 | 3.19 |
| Hemostasis | R-HSA-109582 | 3.98 |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | R-HSA-198933 | 4.7 |
| GO term | GO ID | GO IC |
|---|---|---|
| signaling receptor activity | GO:0038023 | 2.49 |
| enzyme binding | GO:0019899 | 2.27 |
| molecular transducer activity | GO:0060089 | 2.32 |
| macromolecular complex binding | GO:0044877 | 2.61 |
| binding | GO:0005488 | 0.18 |
| signal transducer activity | GO:0004871 | 2.28 |
| ICAM-3 receptor activity | GO:0030369 | 8.64 |
| glycoprotein binding | GO:0001948 | 5.11 |
| cation binding | GO:0043169 | 1.4 |
| ion binding | GO:0043167 | 1.36 |
| protein complex binding | GO:0032403 | 3.09 |
| metal ion binding | GO:0046872 | 1.41 |
| protein kinase binding | GO:0019901 | 3.44 |
| kinase binding | GO:0019900 | 3.32 |
| cell adhesion molecule binding | GO:0050839 | 4.5 |
| carbohydrate derivative binding | GO:0097367 | 2.03 |
| transmembrane signaling receptor activity | GO:0004888 | 2.57 |
| protein binding | GO:0005515 | 0.46 |
| protein dimerization activity | GO:0046983 | 2.72 |
| protein heterodimerization activity | GO:0046982 | 3.64 |
| transmembrane receptor activity | GO:0099600 | 2.53 |
| receptor activity | GO:0004872 | 2.32 |