Gene table of KCNA5 : potassium voltage-gated channel subfamily A member 5

Gene-disease associations table

Disease ID	Disease name	Source of annotation with KCNA5	OMIM link	Number of associated genes	genes
PS178600	PULMONARY HYPERTENSION, PRIMARY	ClinVar	link to OMIM	5	SMAD9, KCNK3, KCNA5, BMPR2, CAV1
PS608583	ATRIAL FIBRILLATION, FAMILIAL	ClinVar, OMIM	link to OMIM	13	SCN3B, NUP155, ABCC9, KCNA5, GJA5, SCN4B, SCN2B, SCN5A, KCNE2, KCNJ2, KCNQ1, NPPA, SCN1B

Download the gene annotation in CSV format

Annotation of the gene KCNA5

Associated genes in ENSEMBL

ENSG00000130037

Associated proteins - SwissProt Accession ID

P22460

Associated PDB IDs

Cytogenetic Band

12p13.32

Tandem repeats annotation

The gene is in the tandem Group 553, together with the genes:

KCNA1

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
Neuronal System	R-HSA-112316	4.82
Voltage gated Potassium channels	R-HSA-1296072	7.56
Potassium Channels	R-HSA-1296071	6.35

Associated GO terms for Molecular function

GO term	GO ID	GO IC
potassium channel activity	GO:0005267	4.94
cation channel activity	GO:0005261	4.04
enzyme binding	GO:0019899	2.27
binding	GO:0005488	0.18
molecular function regulator	GO:0098772	2.51
actinin binding	GO:0042805	6.3
potassium channel inhibitor activity	GO:0019870	7.66
outward rectifier potassium channel activity	GO:0015271	7.44
voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	GO:0086008	7.79
transmembrane transporter activity	GO:0022857	2.82
voltage-gated potassium channel activity involved in SA node cell action potential repolarization	GO:0086090	9.74
voltage-gated cation channel activity	GO:0022843	4.83
channel inhibitor activity	GO:0016248	6.13
channel regulator activity	GO:0016247	4.88
passive transmembrane transporter activity	GO:0022803	3.6
metal ion transmembrane transporter activity	GO:0046873	3.71
voltage-gated potassium channel activity involved in bundle of His cell action potential repolarization	GO:0086087	9.74
ion channel activity	GO:0005216	3.71
voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization	GO:0086089	9.05
alpha-actinin binding	GO:0051393	6.6
voltage-gated potassium channel activity	GO:0005249	5.24
transporter activity	GO:0005215	2.57
potassium channel regulator activity	GO:0015459	5.93
cation transmembrane transporter activity	GO:0008324	3.32
protein kinase binding	GO:0019901	3.44
kinase binding	GO:0019900	3.32
substrate-specific transporter activity	GO:0022892	2.72
delayed rectifier potassium channel activity	GO:0005251	6.15
ion channel inhibitor activity	GO:0008200	6.15
substrate-specific transmembrane transporter activity	GO:0022891	2.9
inorganic cation transmembrane transporter activity	GO:0022890	3.49
voltage-gated ion channel activity	GO:0005244	4.49
cytoskeletal protein binding	GO:0008092	3.02
ion transmembrane transporter activity	GO:0015075	3.04
voltage-gated channel activity	GO:0022832	4.49
monovalent inorganic cation transmembrane transporter activity	GO:0015077	3.87
channel activity	GO:0015267	3.6
scaffold protein binding	GO:0097110	5.93
gated channel activity	GO:0022836	3.96
protein binding	GO:0005515	0.46
receptor binding	GO:0005102	2.43
substrate-specific channel activity	GO:0022838	3.67
potassium ion transmembrane transporter activity	GO:0015079	4.77