| Disease ID | Disease name | Source of annotation with LIPE | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| PS151660 | LIPODYSTROPHY, FAMILIAL PARTIAL | OMIM | link to OMIM | 6 | PPARG, LIPE, PLIN1, CIDEC, LMNA, PPP1R3A |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| Insulin signaling pathway | hsa04910 | 5.55 |
| AMPK signaling pathway | hsa04152 | 5.8 |
| cAMP signaling pathway | hsa04024 | 5.05 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Metabolism of lipids and lipoproteins | R-HSA-556833 | 3.79 |
| Metabolism | R-HSA-1430728 | 2.34 |
| Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis | R-HSA-163560 | 8.66 |
| Lipid digestion, mobilization, and transport | R-HSA-73923 | 7.2 |
| GO term | GO ID | GO IC |
|---|---|---|
| hormone-sensitive lipase activity | GO:0033878 | 9.74 |
| enzyme binding | GO:0019899 | 2.27 |
| triglyceride lipase activity | GO:0004806 | 6.74 |
| hydrolase activity | GO:0016787 | 1.9 |
| catalytic activity | GO:0003824 | 1.05 |
| hydrolase activity, acting on ester bonds | GO:0016788 | 3.1 |
| protein kinase binding | GO:0019901 | 3.44 |
| kinase binding | GO:0019900 | 3.32 |
| binding | GO:0005488 | 0.18 |
| protein binding | GO:0005515 | 0.46 |
| carboxylic ester hydrolase activity | GO:0052689 | 4.81 |
| lipase activity | GO:0016298 | 4.96 |