Gene table of MMP14 : matrix metallopeptidase 14

Gene-disease associations table

Disease ID	Disease name	Source of annotation with MMP14	OMIM link	Number of associated genes	genes
277950	WINCHESTER SYNDROME	ClinVar, OMIM, HUMSAVAR	link to OMIM	1	MMP14

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
TNF signaling pathway	hsa04668	5.96
GnRH signaling pathway	hsa04912	6.18

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
Activation of Matrix Metalloproteinases	R-HSA-1592389	8.03
Extracellular matrix organization	R-HSA-1474244	4.91
Degradation of the extracellular matrix	R-HSA-1474228	6.11
Collagen degradation	R-HSA-1442490	7.03

Associated GO terms for Molecular function

GO term	GO ID	GO IC
binding	GO:0005488	0.18
serine-type endopeptidase activity	GO:0004252	4.4
endopeptidase activity	GO:0004175	3.63
integrin binding	GO:0005178	5.07
macromolecular complex binding	GO:0044877	2.61
zinc ion binding	GO:0008270	2.66
peptidase activity	GO:0008233	3.23
molecular function regulator	GO:0098772	2.51
metallopeptidase activity	GO:0008237	4.5
serine-type peptidase activity	GO:0008236	4.27
cation binding	GO:0043169	1.4
transition metal ion binding	GO:0046914	2.48
ion binding	GO:0043167	1.36
calcium ion binding	GO:0005509	3.17
protein complex binding	GO:0032403	3.09
metal ion binding	GO:0046872	1.41
hydrolase activity	GO:0016787	1.9
metalloendopeptidase activity	GO:0004222	5.02
serine hydrolase activity	GO:0017171	4.26
enzyme regulator activity	GO:0030234	2.85
peptidase regulator activity	GO:0061134	4.37
catalytic activity	GO:0003824	1.05
cell adhesion molecule binding	GO:0050839	4.5
peptidase activity, acting on L-amino acid peptides	GO:0070011	3.26
protein binding	GO:0005515	0.46
peptidase activator activity	GO:0016504	6.13
receptor binding	GO:0005102	2.43
enzyme activator activity	GO:0008047	3.56