| Disease ID | Disease name | Source of annotation with MTNR1B | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| 125853 | DIABETES MELLITUS, NONINSULIN-DEPENDENT | OMIM | link to OMIM | 33 | SLC2A2, HNF4A, TCF7L2, SLC30A8, GPD2, PAX4, PTPN1, SLC2A4, ABCC8, HMGA1, LIPC, NEUROD1, CDKAL1, WFS1, PPARG, RETN, AKT2, IRS2, IL6, IRS1, GCGR, CAPN10, IGF2BP2, INSR, PDX1, MTNR1B, GCK, HNF1B, HNF1A, MAPK8IP1, ENPP1, PPP1R3A, KCNJ11 |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| Circadian entrainment | hsa04713 | 6.11 |
| Neuroactive ligand-receptor interaction | hsa04080 | 4.58 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Signaling by GPCR | R-HSA-372790 | 2.68 |
| G alpha (i) signalling events | R-HSA-418594 | 5.1 |
| Class A/1 (Rhodopsin-like receptors) | R-HSA-373076 | 4.69 |
| GPCR downstream signaling | R-HSA-388396 | 3.07 |
| GPCR ligand binding | R-HSA-500792 | 4.19 |
| Signal Transduction | R-HSA-162582 | 1.78 |
| GO term | GO ID | GO IC |
|---|---|---|
| melatonin receptor activity | GO:0008502 | 8.13 |
| G-protein coupled receptor activity | GO:0004930 | 2.95 |
| signaling receptor activity | GO:0038023 | 2.49 |
| protein binding | GO:0005515 | 0.46 |
| molecular transducer activity | GO:0060089 | 2.32 |
| transmembrane signaling receptor activity | GO:0004888 | 2.57 |
| receptor activity | GO:0004872 | 2.32 |
| signal transducer activity | GO:0004871 | 2.28 |
| transmembrane receptor activity | GO:0099600 | 2.53 |
| binding | GO:0005488 | 0.18 |