| Disease ID | Disease name | Source of annotation with MYC | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| 113970 | BURKITT LYMPHOMA | ClinVar, OMIM | link to OMIM | 1 | MYC |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| Signaling pathways regulating pluripotency of stem cells | hsa04550 | 5.6 |
| Bladder cancer | hsa05219 | 7.38 |
| Endometrial cancer | hsa05213 | 6.81 |
| Colorectal cancer | hsa05210 | 6.52 |
| MAPK signaling pathway | hsa04010 | 4.63 |
| Thyroid cancer | hsa05216 | 7.48 |
| Jak-STAT signaling pathway | hsa04630 | 5.44 |
| Central carbon metabolism in cancer | hsa05230 | 6.7 |
| Epstein-Barr virus infection | hsa05169 | 4.97 |
| HTLV-I infection | hsa05166 | 4.59 |
| Wnt signaling pathway | hsa04310 | 5.49 |
| Hepatitis B | hsa05161 | 5.52 |
| TGF-beta signaling pathway | hsa04350 | 6.41 |
| Proteoglycans in cancer | hsa05205 | 5.02 |
| Cell cycle | hsa04110 | 5.68 |
| MicroRNAs in cancer | hsa05206 | 5.38 |
| Pathways in cancer | hsa05200 | 3.98 |
| Transcriptional misregulation in cancer | hsa05202 | 5.21 |
| Hippo signaling pathway | hsa04390 | 5.37 |
| ErbB signaling pathway | hsa04012 | 6.15 |
| Acute myeloid leukemia | hsa05221 | 6.74 |
| Chronic myeloid leukemia | hsa05220 | 6.48 |
| Thyroid hormone signaling pathway | hsa04919 | 5.82 |
| PI3K-Akt signaling pathway | hsa04151 | 4.21 |
| Small cell lung cancer | hsa05222 | 6.17 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Signaling by NOTCH | R-HSA-157118 | 6.2 |
| Cell Cycle | R-HSA-1640170 | 3.89 |
| binding of TCF/LEF:CTNNB1 to target gene promoters | R-HSA-4411364 | 10.18 |
| Disease | R-HSA-1643685 | 3.33 |
| MAPK family signaling cascades | R-HSA-5683057 | 4.89 |
| Generic Transcription Pathway | R-HSA-212436 | 3.86 |
| Gene Expression | R-HSA-74160 | 2.72 |
| Cell Cycle, Mitotic | R-HSA-69278 | 4.16 |
| Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer | R-HSA-2173793 | 7.56 |
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | R-HSA-2894862 | 7.15 |
| SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription | R-HSA-2173796 | 8.03 |
| Mitotic G1-G1/S phases | R-HSA-453279 | 5.91 |
| Diseases of signal transduction | R-HSA-5663202 | 4.89 |
| MAPK6/MAPK4 signaling | R-HSA-5687128 | 6.54 |
| Signaling by TGF-beta Receptor Complex | R-HSA-170834 | 6.81 |
| Signaling by NOTCH1 | R-HSA-1980143 | 6.81 |
| NOTCH1 Intracellular Domain Regulates Transcription | R-HSA-2122947 | 7.43 |
| Signaling by Wnt | R-HSA-195721 | 4.79 |
| formation of the beta-catenin:TCF transactivating complex | R-HSA-201722 | 7.18 |
| Cyclin A:Cdk2-associated events at S phase entry | R-HSA-69656 | 6.94 |
| G1/S Transition | R-HSA-69206 | 6.21 |
| Signaling by NOTCH1 in Cancer | R-HSA-2644603 | 7.15 |
| Signaling by NOTCH1 PEST Domain Mutants in Cancer | R-HSA-2644602 | 7.15 |
| Cyclin E associated events during G1/S transition | R-HSA-69202 | 6.96 |
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | R-HSA-2644606 | 7.15 |
| S Phase | R-HSA-69242 | 6.02 |
| Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer | R-HSA-2894858 | 7.15 |
| TCF dependent signaling in response to WNT | R-HSA-201681 | 5.36 |
| Signal Transduction | R-HSA-162582 | 1.78 |
| GO term | GO ID | GO IC |
|---|---|---|
| RNA polymerase II regulatory region DNA binding | GO:0001012 | 3.36 |
| core promoter proximal region DNA binding | GO:0001159 | 3.82 |
| transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding | GO:0001077 | 4.31 |
| macromolecular complex binding | GO:0044877 | 2.61 |
| nucleic acid binding transcription factor activity | GO:0001071 | 2.65 |
| nucleic acid binding | GO:0003676 | 1.44 |
| DNA binding | GO:0003677 | 1.92 |
| E-box binding | GO:0070888 | 6.21 |
| heterocyclic compound binding | GO:1901363 | 1.06 |
| repressing transcription factor binding | GO:0070491 | 5.71 |
| sequence-specific DNA binding | GO:0043565 | 2.79 |
| sequence-specific double-stranded DNA binding | GO:1990837 | 3.2 |
| core promoter proximal region sequence-specific DNA binding | GO:0000987 | 3.83 |
| double-stranded DNA binding | GO:0003690 | 3.09 |
| transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding | GO:0000982 | 3.94 |
| RNA polymerase II transcription factor activity, sequence-specific DNA binding | GO:0000981 | 3.29 |
| transcription factor binding | GO:0008134 | 3.46 |
| regulatory region nucleic acid binding | GO:0001067 | 3.03 |
| protein complex binding | GO:0032403 | 3.09 |
| protein dimerization activity | GO:0046983 | 2.72 |
| transcription regulatory region DNA binding | GO:0044212 | 3.03 |
| transcription factor activity, sequence-specific DNA binding | GO:0003700 | 2.65 |
| organic cyclic compound binding | GO:0097159 | 1.05 |
| transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding | GO:0001228 | 3.98 |
| transcription regulatory region sequence-specific DNA binding | GO:0000976 | 3.24 |
| RNA polymerase II regulatory region sequence-specific DNA binding | GO:0000977 | 3.37 |
| protein binding | GO:0005515 | 0.46 |
| regulatory region DNA binding | GO:0000975 | 3.03 |
| RNA polymerase II core promoter proximal region sequence-specific DNA binding | GO:0000978 | 3.88 |
| binding | GO:0005488 | 0.18 |