Gene table of NR0B1 : nuclear receptor subfamily 0 group B member 1

Gene-disease associations table

Disease ID	Disease name	Source of annotation with NR0B1	OMIM link	Number of associated genes	genes
300200	ADRENAL HYPOPLASIA, CONGENITAL	ClinVar, OMIM, HUMSAVAR	link to OMIM	1	NR0B1
PS400044	46,XY SEX REVERSAL	ClinVar, OMIM	link to OMIM	9	AKR1C2, AKR1C4, NR0B1, SRY, MAP3K1, CBX2, NR5A1, DHH, ZFPM2

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Annotation of the gene NR0B1

Associated genes in ENSEMBL

ENSG00000169297

Associated proteins - SwissProt Accession ID

P51843

Associated PDB IDs

4rwv

Cytogenetic Band

Xp21.2

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

It is a TF of the genes:

It is regulated by the following TF:

Associated KEGG pathways

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
Nuclear Receptor transcription pathway	R-HSA-383280	7.31
Generic Transcription Pathway	R-HSA-212436	3.86
Gene Expression	R-HSA-74160	2.72

Associated GO terms for Molecular function

GO term	GO ID	GO IC
signaling receptor activity	GO:0038023	2.49
nucleic acid binding	GO:0003676	1.44
AF-2 domain binding	GO:0050682	8.64
molecular transducer activity	GO:0060089	2.32
transcription factor activity, direct ligand regulated sequence-specific DNA binding	GO:0098531	5.87
binding	GO:0005488	0.18
signal transducer activity	GO:0004871	2.28
DNA binding	GO:0003677	1.92
heterocyclic compound binding	GO:1901363	1.06
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding	GO:0004879	5.87
sequence-specific DNA binding	GO:0043565	2.79
structure-specific DNA binding	GO:0043566	4.98
transcription corepressor activity	GO:0003714	4.33
transcription cofactor activity	GO:0003712	3.44
identical protein binding	GO:0042802	2.63
transcription factor activity, transcription factor binding	GO:0000989	3.36
transcription factor activity, protein binding	GO:0000988	3.35
RNA polymerase II transcription factor activity, sequence-specific DNA binding	GO:0000981	3.29
protein homodimerization activity	GO:0042803	3.16
steroid hormone receptor binding	GO:0035258	5.32
nuclear hormone receptor binding	GO:0035257	4.7
transcription factor binding	GO:0008134	3.46
DNA secondary structure binding	GO:0000217	6.6
protein domain specific binding	GO:0019904	3.32
hormone receptor binding	GO:0051427	4.57
protein dimerization activity	GO:0046983	2.72
transcription factor activity, sequence-specific DNA binding	GO:0003700	2.65
organic cyclic compound binding	GO:0097159	1.05
nucleic acid binding transcription factor activity	GO:0001071	2.65
steroid hormone receptor activity	GO:0003707	5.66
RNA binding	GO:0003723	2.36
protein binding	GO:0005515	0.46
receptor binding	GO:0005102	2.43
DNA hairpin binding	GO:0032448	9.74
receptor activity	GO:0004872	2.32