Gene table of OPRM1 : opioid receptor mu 1

Gene-disease associations table

Disease ID	Disease name	Source of annotation with OPRM1	OMIM link	Number of associated genes	genes
610064	OPIOID DEPENDENCE, SUSCEPTIBILITY TO, 1	ClinVar	link to OMIM	1	OPRM1

Download the gene annotation in CSV format

Annotation of the gene OPRM1

Associated genes in ENSEMBL

ENSG00000112038

Associated proteins - SwissProt Accession ID

P35372

Associated PDB IDs

Cytogenetic Band

6q25.2

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

It is regulated by the following TF:

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
Morphine addiction	hsa05032	6.15
Neuroactive ligand-receptor interaction	hsa04080	4.58
Estrogen signaling pathway	hsa04915	6.11

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
Signaling by GPCR	R-HSA-372790	2.68
G alpha (i) signalling events	R-HSA-418594	5.1
Opioid Signalling	R-HSA-111885	6.64
G-protein activation	R-HSA-202040	8.18
Peptide ligand-binding receptors	R-HSA-375276	5.41
GPCR downstream signaling	R-HSA-388396	3.07
GPCR ligand binding	R-HSA-500792	4.19
Class A/1 (Rhodopsin-like receptors)	R-HSA-373076	4.69
Signal Transduction	R-HSA-162582	1.78

Associated GO terms for Molecular function

GO term	GO ID	GO IC
protein C-terminus binding	GO:0008022	4.5
cation channel activity	GO:0005261	4.04
morphine receptor activity	GO:0038047	9.74
calcium channel activity	GO:0005262	5.03
neuropeptide receptor activity	GO:0008188	5.95
molecular transducer activity	GO:0060089	2.32
binding	GO:0005488	0.18
signal transducer activity	GO:0004871	2.28
beta-endorphin receptor activity	GO:0004979	9.74
melanocortin receptor activity	GO:0004977	7.95
G-protein coupled peptide receptor activity	GO:0008528	4.86
G-protein coupled receptor activity	GO:0004930	2.95
peptide binding	GO:0042277	4.22
neuropeptide binding	GO:0042923	6.65
transmembrane transporter activity	GO:0022857	2.82
divalent inorganic cation transmembrane transporter activity	GO:0072509	4.62
G-protein alpha-subunit binding	GO:0001965	6.6
voltage-gated cation channel activity	GO:0022843	4.83
transporter activity	GO:0005215	2.57
passive transmembrane transporter activity	GO:0022803	3.6
metal ion transmembrane transporter activity	GO:0046873	3.71
G-protein beta-subunit binding	GO:0031681	7.54
filamin binding	GO:0031005	7.17
opioid receptor activity	GO:0004985	7.66
calcium ion transmembrane transporter activity	GO:0015085	4.89
amide binding	GO:0033218	4.14
ion channel activity	GO:0005216	3.71
cation transmembrane transporter activity	GO:0008324	3.32
peptide receptor activity	GO:0001653	4.84
protein domain specific binding	GO:0019904	3.32
voltage-gated calcium channel activity	GO:0005245	6.0
voltage-gated ion channel activity	GO:0005244	4.49
substrate-specific transmembrane transporter activity	GO:0022891	2.9
inorganic cation transmembrane transporter activity	GO:0022890	3.49
substrate-specific transporter activity	GO:0022892	2.72
cytoskeletal protein binding	GO:0008092	3.02
ion transmembrane transporter activity	GO:0015075	3.04
voltage-gated channel activity	GO:0022832	4.49
transmembrane signaling receptor activity	GO:0004888	2.57
channel activity	GO:0015267	3.6
gated channel activity	GO:0022836	3.96
protein binding	GO:0005515	0.46
signaling receptor activity	GO:0038023	2.49
substrate-specific channel activity	GO:0022838	3.67
transmembrane receptor activity	GO:0099600	2.53
receptor activity	GO:0004872	2.32