Gene table of PTPN22 : protein tyrosine phosphatase, non-receptor type 22

Gene-disease associations table

Disease ID	Disease name	Source of annotation with PTPN22	OMIM link	Number of associated genes	genes
152700	SYSTEMIC LUPUS ERYTHEMATOSUS	OMIM, HUMSAVAR	link to OMIM	6	FCGR2A, PTPN22, CTLA4, TREX1, FCGR2B, DNASE1
222100	DIABETES MELLITUS, INSULIN-DEPENDENT	OMIM, HUMSAVAR	link to OMIM	5	FOXP3, HNF1A, OAS1, ITPR3, PTPN22
180300	RHEUMATOID ARTHRITIS	ClinVar, OMIM, HUMSAVAR	link to OMIM	9	IL10, PTPN22, SLC22A4, PADI4, HLA-DRB1, NFKBIL1, IRF5, CIITA, CD244

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

Associated REACTOME pathways

Associated GO terms for Molecular function

GO term	GO ID	GO IC
hydrolase activity	GO:0016787	1.9
enzyme binding	GO:0019899	2.27
ubiquitin protein ligase binding	GO:0031625	4.17
phosphatase activity	GO:0016791	4.11
kinase binding	GO:0019900	3.32
protein tyrosine phosphatase activity	GO:0004725	5.09
SH3 domain binding	GO:0017124	4.98
phosphoprotein phosphatase activity	GO:0004721	4.55
hydrolase activity, acting on ester bonds	GO:0016788	3.1
catalytic activity	GO:0003824	1.05
protein domain specific binding	GO:0019904	3.32
protein binding	GO:0005515	0.46
phosphoric ester hydrolase activity	GO:0042578	3.82
ubiquitin-like protein ligase binding	GO:0044389	4.15
binding	GO:0005488	0.18