Gene table of RARA : retinoic acid receptor alpha

Gene-disease associations table

Disease ID	Disease name	Source of annotation with RARA	OMIM link	Number of associated genes	genes
612376	ACUTE PROMYELOCYTIC LEUKEMIA	OMIM	link to OMIM	2	RARA, NUMA1

Download the gene annotation in CSV format

Annotation of the gene RARA

Associated genes in ENSEMBL

ENSG00000131759

Associated proteins - SwissProt Accession ID

P10276

Associated PDB IDs

Cytogenetic Band

17q21.2

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

It is a TF of the genes:

It is regulated by the following TF:

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
Pathways in cancer	hsa05200	3.98
Acute myeloid leukemia	hsa05221	6.74
Transcriptional misregulation in cancer	hsa05202	5.21

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
Nuclear Receptor transcription pathway	R-HSA-383280	7.31
Generic Transcription Pathway	R-HSA-212436	3.86
Signal Transduction	R-HSA-162582	1.78
Signaling by Retinoic Acid	R-HSA-5362517	7.62
Gene Expression	R-HSA-74160	2.72

Associated GO terms for Molecular function

GO term	GO ID	GO IC
signaling receptor activity	GO:0038023	2.49
nucleic acid binding	GO:0003676	1.44
transcription coactivator activity	GO:0003713	4.04
RNA polymerase II regulatory region DNA binding	GO:0001012	3.36
enzyme binding	GO:0019899	2.27
drug binding	GO:0008144	5.03
molecular transducer activity	GO:0060089	2.32
transcription factor activity, direct ligand regulated sequence-specific DNA binding	GO:0098531	5.87
protein kinase A binding	GO:0051018	6.02
macromolecular complex binding	GO:0044877	2.61
binding	GO:0005488	0.18
signal transducer activity	GO:0004871	2.28
DNA binding	GO:0003677	1.92
mRNA 5'-UTR binding	GO:0048027	7.44
retinoic acid-responsive element binding	GO:0044323	8.64
heterocyclic compound binding	GO:1901363	1.06
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding	GO:0004879	5.87
protein kinase B binding	GO:0043422	7.44
anion binding	GO:0043168	4.17
sequence-specific DNA binding	GO:0043565	2.79
structure-specific DNA binding	GO:0043566	4.98
sequence-specific double-stranded DNA binding	GO:1990837	3.2
transition metal ion binding	GO:0046914	2.48
translation repressor activity, nucleic acid binding	GO:0000900	7.34
transcription factor binding	GO:0008134	3.46
protein heterodimerization activity	GO:0046982	3.64
transcription corepressor activity	GO:0003714	4.33
zinc ion binding	GO:0008270	2.66
transcription cofactor activity	GO:0003712	3.44
ion binding	GO:0043167	1.36
transcription factor activity, transcription factor binding	GO:0000989	3.36
transcription factor activity, protein binding	GO:0000988	3.35
receptor activity	GO:0004872	2.32
actinin binding	GO:0042805	6.3
double-stranded DNA binding	GO:0003690	3.09
metal ion binding	GO:0046872	1.41
histone deacetylase binding	GO:0042826	5.08
retinoid binding	GO:0005501	6.1
RNA polymerase II transcription factor activity, sequence-specific DNA binding	GO:0000981	3.29
RNA binding	GO:0003723	2.36
retinoic acid receptor activity	GO:0003708	7.79
alpha-actinin binding	GO:0051393	6.6
nucleic acid binding transcription factor activity	GO:0001071	2.65
cation binding	GO:0043169	1.4
translation repressor activity	GO:0030371	6.69
regulatory region DNA binding	GO:0000975	3.03
regulatory region nucleic acid binding	GO:0001067	3.03
lipid binding	GO:0008289	3.26
protein kinase binding	GO:0019901	3.44
kinase binding	GO:0019900	3.32
protein domain specific binding	GO:0019904	3.32
translation regulator activity	GO:0045182	6.15
monocarboxylic acid binding	GO:0033293	5.61
protein dimerization activity	GO:0046983	2.72
poly(A) RNA binding	GO:0044822	2.69
transcription regulatory region DNA binding	GO:0044212	3.03
translation regulator activity, nucleic acid binding	GO:0090079	6.79
cytoskeletal protein binding	GO:0008092	3.02
transcription factor activity, sequence-specific DNA binding	GO:0003700	2.65
organic cyclic compound binding	GO:0097159	1.05
carboxylic acid binding	GO:0031406	4.64
chromatin DNA binding	GO:0031490	5.37
steroid hormone receptor activity	GO:0003707	5.66
transcription regulatory region sequence-specific DNA binding	GO:0000976	3.24
RNA polymerase II regulatory region sequence-specific DNA binding	GO:0000977	3.37
protein binding	GO:0005515	0.46
retinoic acid binding	GO:0001972	6.6
receptor binding	GO:0005102	2.43
chromatin binding	GO:0003682	3.64
isoprenoid binding	GO:0019840	6.05
mRNA binding	GO:0003729	4.68