Gene table of SLC19A1 : solute carrier family 19 member 1

Gene-disease associations table

Disease ID	Disease name	Source of annotation with SLC19A1	OMIM link	Number of associated genes	genes
606764	GASTROINTESTINAL STROMAL TUMOR	ClinVar	link to OMIM	10	SDHB, SLC19A1, MTHFR, SDHC, FOLR1, MTRR, KIT, PDGFRA, SHMT1, MTR

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
Vitamin digestion and absorption	hsa04977	8.24

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
Metabolism of vitamins and cofactors	R-HSA-196854	6.54
Metabolism of water-soluble vitamins and cofactors	R-HSA-196849	6.54
Metabolism	R-HSA-1430728	2.34
Metabolism of folate and pterines	R-HSA-196757	9.81

Associated GO terms for Molecular function

GO term	GO ID	GO IC
cofactor transporter activity	GO:0051184	6.69
reduced folate carrier activity	GO:0008518	9.74
modified amino acid binding	GO:0072341	5.56
vitamin transporter activity	GO:0051183	6.56
organic acid binding	GO:0043177	6.6
organic cyclic compound binding	GO:0097159	1.05
folic acid binding	GO:0005542	7.17
folic acid transporter activity	GO:0008517	7.79
vitamin binding	GO:0019842	5.34
transporter activity	GO:0005215	2.57
small molecule binding	GO:0036094	1.89
transmembrane transporter activity	GO:0022857	2.82
methotrexate transporter activity	GO:0015350	9.05
binding	GO:0005488	0.18
amide binding	GO:0033218	4.14
secondary active transmembrane transporter activity	GO:0015291	4.29
heterocyclic compound binding	GO:1901363	1.06
active transmembrane transporter activity	GO:0022804	3.85
drug transporter activity	GO:0090484	6.69