Gene table of SLC22A18 : solute carrier family 22 member 18

Gene-disease associations table

Disease ID	Disease name	Source of annotation with SLC22A18	OMIM link	Number of associated genes	genes
268210	RHABDOMYOSARCOMA, EMBRYONAL, 1	OMIM	link to OMIM	1	SLC22A18
211980	LUNG CANCER	OMIM, HUMSAVAR	link to OMIM	17	RASSF1, PARK2, IRF1, DLEC1, ERBB2, CYP2A6, PPP2R1B, MAP3K8, PIK3CA, BRAF, KRAS, SLC22A18, ERCC6, FASLG, CASP8, MXRA5, EGFR
114480	BREAST CANCER	OMIM	link to OMIM	27	RB1CC1, ESR1, NBN, PALB2, SLC22A18, BRIP1, BCPR, CASP8, FAM175A, TSG101, CHEK2, BARD1, TP53, AKT1, BRCA1, RAD51, PHB, PPM1D, NQO2, ATM, PIK3CA, BRCA2, CDH1, XRCC3, HMMR, KRAS, RAD54L

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
SLC-mediated transmembrane transport	R-HSA-425407	4.95
Organic cation/anion/zwitterion transport	R-HSA-549132	9.18
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds	R-HSA-425366	6.34
Transmembrane transport of small molecules	R-HSA-382551	3.79
Organic cation transport	R-HSA-549127	9.81

Associated GO terms for Molecular function

GO term	GO ID	GO IC
ubiquitin-like protein ligase binding	GO:0044389	4.15
enzyme binding	GO:0019899	2.27
binding	GO:0005488	0.18
monovalent inorganic cation transmembrane transporter activity	GO:0015077	3.87
drug transmembrane transporter activity	GO:0015238	6.85
active transmembrane transporter activity	GO:0022804	3.85
substrate-specific transmembrane transporter activity	GO:0022891	2.9
antiporter activity	GO:0015297	5.33
secondary active transmembrane transporter activity	GO:0015291	4.29
symporter activity	GO:0015293	4.78
transporter activity	GO:0005215	2.57
cation transmembrane transporter activity	GO:0008324	3.32
solute:proton antiporter activity	GO:0015299	6.74
solute:cation antiporter activity	GO:0015298	6.24
ubiquitin protein ligase binding	GO:0031625	4.17
drug:proton antiporter activity	GO:0015307	8.64
inorganic cation transmembrane transporter activity	GO:0022890	3.49
substrate-specific transporter activity	GO:0022892	2.72
ion transmembrane transporter activity	GO:0015075	3.04
transmembrane transporter activity	GO:0022857	2.82
protein binding	GO:0005515	0.46
drug transporter activity	GO:0090484	6.69
hydrogen ion transmembrane transporter activity	GO:0015078	5.01