| Disease ID | Disease name | Source of annotation with SLC2A4 | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| 125853 | DIABETES MELLITUS, NONINSULIN-DEPENDENT | ClinVar, HUMSAVAR | link to OMIM | 33 | SLC2A2, HNF4A, TCF7L2, SLC30A8, GPD2, PAX4, PTPN1, SLC2A4, ABCC8, HMGA1, LIPC, NEUROD1, CDKAL1, WFS1, PPARG, RETN, AKT2, IRS2, IL6, IRS1, GCGR, CAPN10, IGF2BP2, INSR, PDX1, MTNR1B, GCK, HNF1B, HNF1A, MAPK8IP1, ENPP1, PPP1R3A, KCNJ11 |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| Type II diabetes mellitus | hsa04930 | 7.12 |
| Insulin signaling pathway | hsa04910 | 5.55 |
| AMPK signaling pathway | hsa04152 | 5.8 |
| FoxO signaling pathway | hsa04068 | 5.63 |
| Adipocytokine signaling pathway | hsa04920 | 6.6 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Facilitative Na+-independent glucose transporters | R-HSA-428790 | 9.28 |
| Membrane Trafficking | R-HSA-199991 | 5.26 |
| Metabolism of carbohydrates | R-HSA-71387 | 4.93 |
| Transcriptional regulation of white adipocyte differentiation | R-HSA-381340 | 6.7 |
| Transmembrane transport of small molecules | R-HSA-382551 | 3.79 |
| Hexose transport | R-HSA-189200 | 7.43 |
| Metabolism | R-HSA-1430728 | 2.34 |
| SLC-mediated transmembrane transport | R-HSA-425407 | 4.95 |
| Translocation of GLUT4 to the plasma membrane | R-HSA-1445148 | 6.77 |
| Glucose transport | R-HSA-70153 | 7.62 |
| Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds | R-HSA-425366 | 6.34 |
| Developmental Biology | R-HSA-1266738 | 3.48 |
| Vesicle-mediated transport | R-HSA-5653656 | 4.33 |
| GO term | GO ID | GO IC |
|---|---|---|
| substrate-specific transmembrane transporter activity | GO:0022891 | 2.9 |
| glucose transmembrane transporter activity | GO:0005355 | 6.85 |
| substrate-specific transporter activity | GO:0022892 | 2.72 |
| sugar transmembrane transporter activity | GO:0051119 | 6.3 |
| carbohydrate transporter activity | GO:1901476 | 5.95 |
| transporter activity | GO:0005215 | 2.57 |
| D-glucose transmembrane transporter activity | GO:0055056 | 7.66 |
| hexose transmembrane transporter activity | GO:0015149 | 6.79 |
| transmembrane transporter activity | GO:0022857 | 2.82 |
| binding | GO:0005488 | 0.18 |
| protein binding | GO:0005515 | 0.46 |
| monosaccharide transmembrane transporter activity | GO:0015145 | 6.79 |
| carbohydrate transmembrane transporter activity | GO:0015144 | 5.95 |