Gene table of SORL1 : sortilin related receptor 1

Gene-disease associations table

Disease ID	Disease name	Source of annotation with SORL1	OMIM link	Number of associated genes	genes
104300	ALZHEIMER DISEASE	OMIM	link to OMIM	13	HFE, PSEN2, ACE, APBB2, APP, A2M, PAXIP1, NOS3, MPO, PLAU, BLMH, PSEN1, SORL1

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

Associated REACTOME pathways

Associated GO terms for Molecular function

GO term	GO ID	GO IC
lipoprotein particle binding	GO:0071813	6.56
beta-amyloid binding	GO:0001540	6.21
protein binding	GO:0005515	0.46
protein-lipid complex binding	GO:0071814	6.56
ADP-ribosylation factor binding	GO:0030306	7.79
amide binding	GO:0033218	4.14
GTPase binding	GO:0051020	4.05
enzyme binding	GO:0019899	2.27
peptide binding	GO:0042277	4.22
molecular transducer activity	GO:0060089	2.32
transmembrane signaling receptor activity	GO:0004888	2.57
macromolecular complex binding	GO:0044877	2.61
binding	GO:0005488	0.18
signal transducer activity	GO:0004871	2.28
receptor activity	GO:0004872	2.32
signaling receptor activity	GO:0038023	2.49
small GTPase binding	GO:0031267	4.13
transmembrane receptor activity	GO:0099600	2.53
low-density lipoprotein particle binding	GO:0030169	7.03