Gene table of SOST : sclerostin

Gene-disease associations table

Disease IDDisease nameSource of annotation with SOSTOMIM linkNumber of associated genesgenes
PS269500SCLEROSTEOSISClinVar, OMIM, HUMSAVAR link to OMIM 2LRP4, SOST
122860CRANIODIAPHYSEAL DYSPLASIA, AUTOSOMAL DOMINANTClinVar, OMIM, HUMSAVAR link to OMIM 1SOST
239100HYPEROSTOSIS CORTICALIS GENERALISATAOMIM link to OMIM 1SOST

Download the gene annotation in CSV format

Annotation of the gene SOST

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST

It is regulated by the following TF:

Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Wnt signaling pathwayhsa043105.49
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
TCF dependent signaling in response to WNTR-HSA-2016815.36
Signaling by WntR-HSA-1957214.79
negative regulation of TCF-dependent signaling by WNT ligand antagonistsR-HSA-37724709.08
Signal TransductionR-HSA-1625821.78
Associated GO terms for Molecular function
GO termGO IDGO IC
sulfur compound bindingGO:19016814.32
carbohydrate derivative bindingGO:00973672.03
transcription factor bindingGO:00081343.46
glycosaminoglycan bindingGO:00055394.42
bindingGO:00054880.18
protein bindingGO:00055150.46
heparin bindingGO:00082014.68