Gene table of TNFAIP3 : TNF alpha induced protein 3

Gene-disease associations table

Disease ID	Disease name	Source of annotation with TNFAIP3	OMIM link	Number of associated genes	genes
616744	AUTOINFLAMMATORY SYNDROME, FAMILIAL, BEHCET-LIKE	ClinVar, OMIM	link to OMIM	1	TNFAIP3

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
TNF signaling pathway	hsa04668	5.96
NF-kappa B signaling pathway	hsa04064	6.21
NOD-like receptor signaling pathway	hsa04621	6.88
Measles	hsa05162	5.6
Epstein-Barr virus infection	hsa05169	4.97

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
Innate Immune System	R-HSA-168249	3.17
TNFR1-induced proapoptotic signaling	R-HSA-5357786	9.28
Immune System	R-HSA-168256	2.37
Death Receptor Signalling	R-HSA-73887	8.52
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways	R-HSA-168643	7.31
RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways	R-HSA-168928	6.7
TNF signaling	R-HSA-75893	9.08
NOD1/2 Signaling Pathway	R-HSA-168638	7.85
Negative regulators of RIG-I/MDA5 signaling	R-HSA-936440	7.98
Signal Transduction	R-HSA-162582	1.78

Associated GO terms for Molecular function

GO term	GO ID	GO IC
polyubiquitin binding	GO:0031593	5.98
ubiquitinyl hydrolase activity	GO:0101005	5.07
enzyme binding	GO:0019899	2.27
binding	GO:0005488	0.18
nucleic acid binding	GO:0003676	1.44
DNA binding	GO:0003677	1.92
peptidase activity	GO:0008233	3.23
heterocyclic compound binding	GO:1901363	1.06
ubiquitin-like protein transferase activity	GO:0019787	3.69
cation binding	GO:0043169	1.4
ubiquitin-like protein-specific protease activity	GO:0019783	4.97
transition metal ion binding	GO:0046914	2.48
ligase activity	GO:0016874	3.72
ion binding	GO:0043167	1.36
transferase activity	GO:0016740	1.95
peptidase activity, acting on L-amino acid peptides	GO:0070011	3.26
protease binding	GO:0002020	5.08
K63-linked polyubiquitin binding	GO:0070530	6.79
metal ion binding	GO:0046872	1.41
hydrolase activity	GO:0016787	1.9
kinase binding	GO:0019900	3.32
cysteine-type peptidase activity	GO:0008234	4.51
ubiquitin-protein transferase activity	GO:0004842	3.73
thiol-dependent ubiquitinyl hydrolase activity	GO:0036459	5.07
protein self-association	GO:0043621	5.93
catalytic activity	GO:0003824	1.05
organic cyclic compound binding	GO:0097159	1.05
ubiquitin-like protein binding	GO:0032182	4.93
thiol-dependent ubiquitin-specific protease activity	GO:0004843	5.43
ubiquitin binding	GO:0043130	5.09
protein binding	GO:0005515	0.46
zinc ion binding	GO:0008270	2.66