Gene table of TNFRSF11A : TNF receptor superfamily member 11a

Gene-disease associations table

Disease IDDisease nameSource of annotation with TNFRSF11AOMIM linkNumber of associated genesgenes
PS259700OSTEOPETROSIS, AUTOSOMAL RECESSIVEClinVar, OMIM, HUMSAVAR link to OMIM 8TNFRSF11A, TNFSF11, SNX10, PLEKHM1, CA2, CLCN7, OSTM1, TCIRG1
174810FAMILIAL EXPANSILE OSTEOLYSISClinVar, OMIM link to OMIM 1TNFRSF11A
PS167250PAGET DISEASE OF BONEClinVar, OMIM link to OMIM 4TNFRSF11A, SQSTM1, TNFRSF11B, ZNF687

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Annotation of the gene TNFRSF11A

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST

It is regulated by the following TF:

Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Rheumatoid arthritishsa053236.05
NF-kappa B signaling pathwayhsa040646.21
Prolactin signaling pathwayhsa049176.6
Cytokine-cytokine receptor interactionhsa040604.67
Osteoclast differentiationhsa043805.64
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
Cytokine Signaling in Immune systemR-HSA-12802153.74
TNFR2 non-canonical NF-kB pathwayR-HSA-56685416.4
Immune SystemR-HSA-1682562.37
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathwayR-HSA-56765948.89
Associated GO terms for Molecular function
GO termGO IDGO IC
bindingGO:00054880.18
cation bindingGO:00431691.4
signaling receptor activityGO:00380232.49
protein bindingGO:00055150.46
molecular transducer activityGO:00600892.32
cytokine bindingGO:00199555.21
ion bindingGO:00431671.36
death receptor activityGO:00050356.56
transmembrane signaling receptor activityGO:00048882.57
tumor necrosis factor-activated receptor activityGO:00050316.56
signal transducer activityGO:00048712.28
metal ion bindingGO:00468721.41
transmembrane receptor activityGO:00996002.53
receptor activityGO:00048722.32