| Disease ID | Disease name | Source of annotation with VEGFC | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| PS153100 | LYMPHEDEMA, HEREDITARY | ClinVar, OMIM | link to OMIM | 3 | FLT4, VEGFC, GJC2 |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| Pathways in cancer | hsa05200 | 3.98 |
| Rap1 signaling pathway | hsa04015 | 4.97 |
| Ras signaling pathway | hsa04014 | 4.9 |
| Focal adhesion | hsa04510 | 4.92 |
| TNF signaling pathway | hsa04668 | 5.96 |
| Cytokine-cytokine receptor interaction | hsa04060 | 4.67 |
| PI3K-Akt signaling pathway | hsa04151 | 4.21 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| VEGF binds to VEGFR leading to receptor dimerization | R-HSA-195399 | 9.98 |
| Platelet degranulation | R-HSA-114608 | 6.68 |
| Signaling by VEGF | R-HSA-194138 | 4.66 |
| Platelet activation, signaling and aggregation | R-HSA-76002 | 5.15 |
| VEGF ligand-receptor interactions | R-HSA-194313 | 9.98 |
| Response to elevated platelet cytosolic Ca2+ | R-HSA-76005 | 6.59 |
| Hemostasis | R-HSA-109582 | 3.98 |
| Signal Transduction | R-HSA-162582 | 1.78 |
| GO term | GO ID | GO IC |
|---|---|---|
| cytokine receptor binding | GO:0005126 | 4.14 |
| chemoattractant activity | GO:0042056 | 6.48 |
| growth factor activity | GO:0008083 | 4.66 |
| growth factor receptor binding | GO:0070851 | 4.87 |
| vascular endothelial growth factor receptor binding | GO:0005172 | 7.54 |
| vascular endothelial growth factor receptor 3 binding | GO:0043185 | 9.74 |
| binding | GO:0005488 | 0.18 |
| protein binding | GO:0005515 | 0.46 |
| receptor binding | GO:0005102 | 2.43 |