| Disease ID | Disease name | Source of annotation with ACOX1 | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| 264470 | PEROXISOMAL ACYL-COA OXIDASE DEFICIENCY | OMIM, HUMSAVAR | link to OMIM | 1 | ACOX1 |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| alpha-Linolenic acid metabolism | hsa00592 | 8.12 |
| PPAR signaling pathway | hsa03320 | 6.56 |
| Metabolic pathways | hsa01100 | 2.49 |
| Fatty acid degradation | hsa00071 | 7.15 |
| cAMP signaling pathway | hsa04024 | 5.05 |
| Peroxisome | hsa04146 | 6.34 |
| Fatty acid metabolism | hsa01212 | 7.07 |
| Biosynthesis of unsaturated fatty acids | hsa01040 | 8.38 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| PPARA activates gene expression | R-HSA-1989781 | 6.18 |
| Peroxisomal lipid metabolism | R-HSA-390918 | 8.59 |
| Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) | R-HSA-400206 | 6.14 |
| alpha-linolenic acid (ALA) metabolism | R-HSA-2046106 | 9.28 |
| alpha-linolenic (omega3) and linoleic (omega6) acid metabolism | R-HSA-2046104 | 9.28 |
| Beta-oxidation of very long chain fatty acids | R-HSA-390247 | 10.4 |
| Metabolism | R-HSA-1430728 | 2.34 |
| Fatty acid, triacylglycerol, and ketone body metabolism | R-HSA-535734 | 5.44 |
| Metabolism of lipids and lipoproteins | R-HSA-556833 | 3.79 |
| GO term | GO ID | GO IC |
|---|---|---|
| binding | GO:0005488 | 0.18 |
| heterocyclic compound binding | GO:1901363 | 1.06 |
| nucleoside phosphate binding | GO:1901265 | 1.96 |
| oxidoreductase activity | GO:0016491 | 3.12 |
| sulfur compound binding | GO:1901681 | 4.32 |
| coenzyme binding | GO:0050662 | 4.53 |
| flavin adenine dinucleotide binding | GO:0050660 | 5.41 |
| oxidoreductase activity, acting on the CH-CH group of donors | GO:0016627 | 5.66 |
| fatty-acyl-CoA binding | GO:0000062 | 6.3 |
| nucleotide binding | GO:0000166 | 1.96 |
| FAD binding | GO:0071949 | 7.03 |
| oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor | GO:0052890 | 6.97 |
| small molecule binding | GO:0036094 | 1.89 |
| catalytic activity | GO:0003824 | 1.05 |
| PDZ domain binding | GO:0030165 | 5.22 |
| cofactor binding | GO:0048037 | 4.16 |
| protein domain specific binding | GO:0019904 | 3.32 |
| receptor binding | GO:0005102 | 2.43 |
| electron carrier activity | GO:0009055 | 4.97 |
| protein N-terminus binding | GO:0047485 | 5.11 |
| organic cyclic compound binding | GO:0097159 | 1.05 |
| oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor | GO:0016634 | 7.54 |
| GO:0016401 | 8.64 | |
| protein binding | GO:0005515 | 0.46 |
| acyl-CoA dehydrogenase activity | GO:0003995 | 6.91 |
| GO:0003997 | 7.95 |