Gene table of ADAMTS13 : ADAM metallopeptidase with thrombospondin type 1 motif 13

Gene-disease associations table

Disease ID	Disease name	Source of annotation with ADAMTS13	OMIM link	Number of associated genes	genes
274150	THROMBOTIC THROMBOCYTOPENIC PURPURA, CONGENITAL	ClinVar, OMIM, HUMSAVAR	link to OMIM	1	ADAMTS13

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
Post-translational protein modification	R-HSA-597592	4.54
O-glycosylation of TSR domain-containing proteins	R-HSA-5173214	7.7
Metabolism of proteins	R-HSA-392499	3.41
O-linked glycosylation	R-HSA-5173105	6.3

Associated GO terms for Molecular function

GO term	GO ID	GO IC
integrin binding	GO:0005178	5.07
endopeptidase activity	GO:0004175	3.63
metalloendopeptidase activity	GO:0004222	5.02
transition metal ion binding	GO:0046914	2.48
hydrolase activity	GO:0016787	1.9
zinc ion binding	GO:0008270	2.66
cation binding	GO:0043169	1.4
ion binding	GO:0043167	1.36
catalytic activity	GO:0003824	1.05
cell adhesion molecule binding	GO:0050839	4.5
peptidase activity, acting on L-amino acid peptides	GO:0070011	3.26
macromolecular complex binding	GO:0044877	2.61
binding	GO:0005488	0.18
protein binding	GO:0005515	0.46
protein complex binding	GO:0032403	3.09
peptidase activity	GO:0008233	3.23
metal ion binding	GO:0046872	1.41
receptor binding	GO:0005102	2.43
metallopeptidase activity	GO:0008237	4.5
calcium ion binding	GO:0005509	3.17