Gene table of ALDOB : aldolase, fructose-bisphosphate B

Gene-disease associations table

Disease ID	Disease name	Source of annotation with ALDOB	OMIM link	Number of associated genes	genes
229600	FRUCTOSE INTOLERANCE, HEREDITARY	ClinVar, OMIM, HUMSAVAR	link to OMIM	1	ALDOB

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
Carbon metabolism	hsa01200	6.03
Metabolic pathways	hsa01100	2.49
Pentose phosphate pathway	hsa00030	7.86
Fructose and mannose metabolism	hsa00051	7.72
Biosynthesis of amino acids	hsa01230	6.58
Glycolysis / Gluconeogenesis	hsa00010	6.64

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
Hereditary fructose intolerance	R-HSA-5657560	12.98
Metabolism of carbohydrates	R-HSA-71387	4.93
Glycolysis	R-HSA-70171	8.03
Diseases of carbohydrate metabolism	R-HSA-5663084	8.28
Diseases of metabolism	R-HSA-5668914	6.57
Fructose metabolism	R-HSA-5652084	10.66
Metabolism	R-HSA-1430728	2.34
Fructose catabolism	R-HSA-70350	11.4
Gluconeogenesis	R-HSA-70263	8.03
Disease	R-HSA-1643685	3.33
Glucose metabolism	R-HSA-70326	6.77

Associated GO terms for Molecular function

GO term	GO ID	GO IC
ammonium ion binding	GO:0070405	5.81
identical protein binding	GO:0042802	2.63
	GO:0004332	8.64
fructose binding	GO:0070061	8.13
cytoskeletal protein binding	GO:0008092	3.02
ATPase binding	GO:0051117	5.41
lyase activity	GO:0016829	4.53
carbon-carbon lyase activity	GO:0016830	5.81
carbohydrate binding	GO:0030246	4.17
enzyme binding	GO:0019899	2.27
ion binding	GO:0043167	1.36
	GO:0061609	9.74
aldehyde-lyase activity	GO:0016832	7.54
cation binding	GO:0043169	1.4
small molecule binding	GO:0036094	1.89
binding	GO:0005488	0.18
protein binding	GO:0005515	0.46
catalytic activity	GO:0003824	1.05
phosphatidylcholine binding	GO:0031210	6.69
monosaccharide binding	GO:0048029	5.85