Gene table of ATP2A1 : ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1

Gene-disease associations table

Disease ID	Disease name	Source of annotation with ATP2A1	OMIM link	Number of associated genes	genes
601003	BRODY MYOPATHY	OMIM, HUMSAVAR	link to OMIM	1	ATP2A1

Download the gene annotation in CSV format

Annotation of the gene ATP2A1

Associated genes in ENSEMBL

ENSG00000196296

Associated proteins - SwissProt Accession ID

O14983

Associated PDB IDs

Cytogenetic Band

16p11.2

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
cGMP-PKG signaling pathway	hsa04022	5.32
Calcium signaling pathway	hsa04020	5.22
Alzheimer's disease	hsa05010	5.34
Pancreatic secretion	hsa04972	6.07

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
Pre-NOTCH Expression and Processing	R-HSA-1912422	7.49
Ion channel transport	R-HSA-983712	5.34
Platelet calcium homeostasis	R-HSA-418360	8.73
Ion transport by P-type ATPases	R-HSA-936837	7.46
Transmembrane transport of small molecules	R-HSA-382551	3.79
Platelet homeostasis	R-HSA-418346	6.68
Pre-NOTCH Processing in Golgi	R-HSA-1912420	8.81
Reduction of cytosolic Ca++ levels	R-HSA-418359	9.66
Signaling by NOTCH	R-HSA-157118	6.2
Hemostasis	R-HSA-109582	3.98
Signal Transduction	R-HSA-162582	1.78

Associated GO terms for Molecular function

GO term	GO ID	GO IC
hydrolase activity	GO:0016787	1.9
purine ribonucleoside triphosphate binding	GO:0035639	2.22
cation binding	GO:0043169	1.4
binding	GO:0005488	0.18
ATPase activity	GO:0016887	3.65
nucleotide binding	GO:0000166	1.96
heterocyclic compound binding	GO:1901363	1.06
nucleoside phosphate binding	GO:1901265	1.96
nucleoside binding	GO:0001882	2.21
ATPase coupled ion transmembrane transporter activity	GO:0042625	5.46
ATPase activity, coupled to transmembrane movement of substances	GO:0042626	5.06
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	GO:0016820	5.03
ATPase activity, coupled	GO:0042623	3.97
protein dimerization activity	GO:0046983	2.72
ion binding	GO:0043167	1.36
primary active transmembrane transporter activity	GO:0015399	4.98
identical protein binding	GO:0042802	2.63
calcium ion binding	GO:0005509	3.17
ribonucleoside binding	GO:0032549	2.22
purine nucleotide binding	GO:0017076	2.19
metal ion transmembrane transporter activity	GO:0046873	3.71
metal ion binding	GO:0046872	1.41
ATP binding	GO:0005524	2.43
protein homodimerization activity	GO:0042803	3.16
divalent inorganic cation transmembrane transporter activity	GO:0072509	4.62
protein binding	GO:0005515	0.46
calcium ion transmembrane transporter activity	GO:0015085	4.89
transporter activity	GO:0005215	2.57
cation transmembrane transporter activity	GO:0008324	3.32
nucleoside-triphosphatase activity	GO:0017111	3.09
small molecule binding	GO:0036094	1.89
catalytic activity	GO:0003824	1.05
calcium-transporting ATPase activity	GO:0005388	7.44
substrate-specific transmembrane transporter activity	GO:0022891	2.9
inorganic cation transmembrane transporter activity	GO:0022890	3.49
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	GO:0016818	3.03
substrate-specific transporter activity	GO:0022892	2.72
adenyl nucleotide binding	GO:0030554	2.4
carbohydrate derivative binding	GO:0097367	2.03
organic cyclic compound binding	GO:0097159	1.05
ATPase activity, coupled to movement of substances	GO:0043492	4.93
hydrolase activity, acting on acid anhydrides	GO:0016817	3.03
cation-transporting ATPase activity	GO:0019829	5.64
ion transmembrane transporter activity	GO:0015075	3.04
pyrophosphatase activity	GO:0016462	3.04
transmembrane transporter activity	GO:0022857	2.82
purine ribonucleoside binding	GO:0032550	2.22
adenyl ribonucleotide binding	GO:0032559	2.41
purine nucleoside binding	GO:0001883	2.22
active ion transmembrane transporter activity	GO:0022853	5.06
active transmembrane transporter activity	GO:0022804	3.85
purine ribonucleotide binding	GO:0032555	2.2
ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism	GO:0015662	6.24
P-P-bond-hydrolysis-driven transmembrane transporter activity	GO:0015405	4.98
ribonucleotide binding	GO:0032553	2.19