| Disease ID | Disease name | Source of annotation with CCT5 | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| 256840 | NEUROPATHY, HEREDITARY SENSORY, WITH SPASTIC PARAPLEGIA, AUTOSOMAL RECESSIVE | OMIM, HUMSAVAR | link to OMIM | 1 | CCT5 |
Download the gene annotation in CSV format
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Protein folding | R-HSA-391251 | 7.23 |
| Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding | R-HSA-389958 | 8.23 |
| Prefoldin mediated transfer of substrate to CCT/TriC | R-HSA-389957 | 8.28 |
| Organelle biogenesis and maintenance | R-HSA-1852241 | 4.63 |
| Metabolism of proteins | R-HSA-392499 | 3.41 |
| Folding of actin by CCT/TriC | R-HSA-390450 | 9.81 |
| Formation of tubulin folding intermediates by CCT/TriC | R-HSA-389960 | 8.66 |
| Cargo trafficking to the periciliary membrane | R-HSA-5620920 | 7.31 |
| Association of TriC/CCT with target proteins during biosynthesis | R-HSA-390471 | 8.12 |
| BBSome-mediated cargo-targeting to cilium | R-HSA-5620922 | 8.46 |
| Assembly of the primary cilium | R-HSA-5617833 | 5.44 |
| Chaperonin-mediated protein folding | R-HSA-390466 | 7.4 |
| GO term | GO ID | GO IC |
|---|---|---|
| purine ribonucleoside triphosphate binding | GO:0035639 | 2.22 |
| beta-tubulin binding | GO:0048487 | 6.13 |
| binding | GO:0005488 | 0.18 |
| heterocyclic compound binding | GO:1901363 | 1.06 |
| purine nucleoside binding | GO:0001883 | 2.22 |
| nucleoside binding | GO:0001882 | 2.21 |
| unfolded protein binding | GO:0051082 | 5.13 |
| nucleotide binding | GO:0000166 | 1.96 |
| nucleoside phosphate binding | GO:1901265 | 1.96 |
| ribonucleoside binding | GO:0032549 | 2.22 |
| purine nucleotide binding | GO:0017076 | 2.19 |
| ATP binding | GO:0005524 | 2.43 |
| G-protein beta-subunit binding | GO:0031681 | 7.54 |
| tubulin binding | GO:0015631 | 4.1 |
| small molecule binding | GO:0036094 | 1.89 |
| cytoskeletal protein binding | GO:0008092 | 3.02 |
| carbohydrate derivative binding | GO:0097367 | 2.03 |
| organic cyclic compound binding | GO:0097159 | 1.05 |
| adenyl nucleotide binding | GO:0030554 | 2.4 |
| adenyl ribonucleotide binding | GO:0032559 | 2.41 |
| protein binding | GO:0005515 | 0.46 |
| purine ribonucleotide binding | GO:0032555 | 2.2 |
| purine ribonucleoside binding | GO:0032550 | 2.22 |
| ribonucleotide binding | GO:0032553 | 2.19 |