Gene table of CERS3 : ceramide synthase 3

Gene-disease associations table

Disease ID	Disease name	Source of annotation with CERS3	OMIM link	Number of associated genes	genes
PS242300	ICHTHYOSIS, CONGENITAL, AUTOSOMAL RECESSIVE	ClinVar, OMIM	link to OMIM	10	PNPLA1, ST14, ABCA12, NIPAL4, ALOXE3, LIPN, ALOX12B, CYP4F22, CERS3, TGM1

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
Metabolic pathways	hsa01100	2.49
Sphingolipid metabolism	hsa00600	7.15

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
Metabolism of lipids and lipoproteins	R-HSA-556833	3.79
Sphingolipid metabolism	R-HSA-428157	6.79
Metabolism	R-HSA-1430728	2.34
Sphingolipid de novo biosynthesis	R-HSA-1660661	7.98

Associated GO terms for Molecular function

GO term	GO ID	GO IC
N-acyltransferase activity	GO:0016410	5.08
organic cyclic compound binding	GO:0097159	1.05
catalytic activity	GO:0003824	1.05
transferase activity	GO:0016740	1.95
transferase activity, transferring acyl groups	GO:0016746	4.2
binding	GO:0005488	0.18
nucleic acid binding	GO:0003676	1.44
DNA binding	GO:0003677	1.92
sphingosine N-acyltransferase activity	GO:0050291	7.79
heterocyclic compound binding	GO:1901363	1.06
transferase activity, transferring acyl groups other than amino-acyl groups	GO:0016747	4.37