| Disease ID | Disease name | Source of annotation with CYC1 | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| 615453 | MITOCHONDRIAL COMPLEX III DEFICIENCY, NUCLEAR TYPE 6 | ClinVar, OMIM, HUMSAVAR | link to OMIM | 1 | CYC1 |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| Oxidative phosphorylation | hsa00190 | 5.69 |
| Cardiac muscle contraction | hsa04260 | 6.34 |
| Metabolic pathways | hsa01100 | 2.49 |
| Non-alcoholic fatty liver disease (NAFLD) | hsa04932 | 5.51 |
| Huntington's disease | hsa05016 | 5.17 |
| Alzheimer's disease | hsa05010 | 5.34 |
| Parkinson's disease | hsa05012 | 5.59 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Respiratory electron transport | R-HSA-611105 | 6.44 |
| Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. | R-HSA-163200 | 6.12 |
| Mitochondrial protein import | R-HSA-1268020 | 7.28 |
| The citric acid (TCA) cycle and respiratory electron transport | R-HSA-1428517 | 5.71 |
| Metabolism of proteins | R-HSA-392499 | 3.41 |
| Metabolism | R-HSA-1430728 | 2.34 |
| GO term | GO ID | GO IC |
|---|---|---|
| cation binding | GO:0043169 | 1.4 |
| heme binding | GO:0020037 | 4.86 |
| tetrapyrrole binding | GO:0046906 | 4.8 |
| organic cyclic compound binding | GO:0097159 | 1.05 |
| ion binding | GO:0043167 | 1.36 |
| binding | GO:0005488 | 0.18 |
| electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity | GO:0045155 | 9.05 |
| metal ion binding | GO:0046872 | 1.41 |
| heterocyclic compound binding | GO:1901363 | 1.06 |
| electron carrier activity | GO:0009055 | 4.97 |