Disease ID | Disease name | Source of annotation with CYP26C1 | OMIM link | Number of associated genes | genes |
---|---|---|---|---|---|
PS136500 | FOCAL FACIAL DERMAL DYSPLASIA | ClinVar, OMIM | link to OMIM | 2 | CYP26C1, TWIST2 |
Download the gene annotation in CSV format
KEGG pathway | KEGG ID | KEGG IC |
---|---|---|
Retinol metabolism | hsa00830 | 6.79 |
Metabolic pathways | hsa01100 | 2.49 |
REACTOME pathway | REACTOME ID | REACTOME IC |
---|---|---|
RA biosynthesis pathway | R-HSA-5365859 | 8.59 |
Cytochrome P450 - arranged by substrate type | R-HSA-211897 | 7.08 |
Biological oxidations | R-HSA-211859 | 5.55 |
Vitamins | R-HSA-211916 | 10.4 |
Defective CYP26C1 causes Focal facial dermal dysplasia 4 (FFDD4) | R-HSA-5579004 | 12.98 |
Diseases of metabolism | R-HSA-5668914 | 6.57 |
Phase 1 - Functionalization of compounds | R-HSA-211945 | 6.7 |
Metabolism | R-HSA-1430728 | 2.34 |
Disease | R-HSA-1643685 | 3.33 |
Signal Transduction | R-HSA-162582 | 1.78 |
Metabolic disorders of biological oxidation enzymes | R-HSA-5579029 | 7.85 |
Signaling by Retinoic Acid | R-HSA-5362517 | 7.62 |
GO term | GO ID | GO IC |
---|---|---|
monooxygenase activity | GO:0004497 | 5.1 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | GO:0016705 | 4.65 |
isoprenoid binding | GO:0019840 | 6.05 |
binding | GO:0005488 | 0.18 |
heterocyclic compound binding | GO:1901363 | 1.06 |
oxidoreductase activity | GO:0016491 | 3.12 |
anion binding | GO:0043168 | 4.17 |
cation binding | GO:0043169 | 1.4 |
transition metal ion binding | GO:0046914 | 2.48 |
retinoic acid 4-hydroxylase activity | GO:0008401 | 8.35 |
ion binding | GO:0043167 | 1.36 |
iron ion binding | GO:0005506 | 4.65 |
metal ion binding | GO:0046872 | 1.41 |
retinoid binding | GO:0005501 | 6.1 |
heme binding | GO:0020037 | 4.86 |
lipid binding | GO:0008289 | 3.26 |
catalytic activity | GO:0003824 | 1.05 |
monocarboxylic acid binding | GO:0033293 | 5.61 |
tetrapyrrole binding | GO:0046906 | 4.8 |
organic cyclic compound binding | GO:0097159 | 1.05 |
carboxylic acid binding | GO:0031406 | 4.64 |
retinoic acid binding | GO:0001972 | 6.6 |