Gene table of CYP2B6 : cytochrome P450 family 2 subfamily B member 6

Gene-disease associations table

Disease IDDisease nameSource of annotation with CYP2B6OMIM linkNumber of associated genesgenes
614546EFAVIRENZ, POOR METABOLISM OFOMIM link to OMIM 1CYP2B6

Download the gene annotation in CSV format

Annotation of the gene CYP2B6

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation

The gene is in the tandem Group 849, together with the genes:

Transcription regulation as annotated in TRRUST

It is regulated by the following TF:

Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Retinol metabolismhsa008306.79
Arachidonic acid metabolismhsa005906.79
Drug metabolism - cytochrome P450hsa009826.6
Metabolic pathwayshsa011002.49
Metabolism of xenobiotics by cytochrome P450hsa009806.48
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
XenobioticsR-HSA-2119818.66
Fatty acidsR-HSA-2119359.08
Biological oxidationsR-HSA-2118595.55
CYP2E1 reactionsR-HSA-2119999.52
Cytochrome P450 - arranged by substrate typeR-HSA-2118977.08
Phase 1 - Functionalization of compoundsR-HSA-2119456.7
MetabolismR-HSA-14307282.34
Associated GO terms for Molecular function
GO termGO IDGO IC
oxidoreductase activityGO:00164913.12
cation bindingGO:00431691.4
monooxygenase activityGO:00044975.1
oxygen bindingGO:00198255.89
transition metal ion bindingGO:00469142.48
heme bindingGO:00200374.86
tetrapyrrole bindingGO:00469064.8
metal ion bindingGO:00468721.41
organic cyclic compound bindingGO:00971591.05
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygenGO:00167054.65
ion bindingGO:00431671.36
aromatase activityGO:00703306.56
catalytic activityGO:00038241.05
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygenGO:00167126.37
bindingGO:00054880.18
iron ion bindingGO:00055064.65
steroid hydroxylase activityGO:00083956.3
arachidonic acid epoxygenase activityGO:00083927.03
heterocyclic compound bindingGO:19013631.06
arachidonic acid monooxygenase activityGO:00083917.03