Gene table of CYP2D6 : cytochrome P450 family 2 subfamily D member 6

Gene-disease associations table

Disease ID	Disease name	Source of annotation with CYP2D6	OMIM link	Number of associated genes	genes
608902	DRUG METABOLISM, POOR, CYP2D6-RELATED	OMIM	link to OMIM	1	CYP2D6

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
Metabolism of xenobiotics by cytochrome P450	hsa00980	6.48
Drug metabolism - cytochrome P450	hsa00982	6.6
Serotonergic synapse	hsa04726	5.84

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
Xenobiotics	R-HSA-211981	8.66
Fatty acids	R-HSA-211935	9.08
Biological oxidations	R-HSA-211859	5.55
CYP2E1 reactions	R-HSA-211999	9.52
Cytochrome P450 - arranged by substrate type	R-HSA-211897	7.08
Phase 1 - Functionalization of compounds	R-HSA-211945	6.7
Metabolism	R-HSA-1430728	2.34
Miscellaneous substrates	R-HSA-211958	9.4

Associated GO terms for Molecular function

GO term	GO ID	GO IC
oxidoreductase activity	GO:0016491	3.12
cation binding	GO:0043169	1.4
monooxygenase activity	GO:0004497	5.1
oxygen binding	GO:0019825	5.89
transition metal ion binding	GO:0046914	2.48
heme binding	GO:0020037	4.86
tetrapyrrole binding	GO:0046906	4.8
metal ion binding	GO:0046872	1.41
organic cyclic compound binding	GO:0097159	1.05
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	GO:0016705	4.65
ion binding	GO:0043167	1.36
drug binding	GO:0008144	5.03
catalytic activity	GO:0003824	1.05
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	GO:0016712	6.37
aromatase activity	GO:0070330	6.56
binding	GO:0005488	0.18
iron ion binding	GO:0005506	4.65
steroid hydroxylase activity	GO:0008395	6.3
arachidonic acid epoxygenase activity	GO:0008392	7.03
heterocyclic compound binding	GO:1901363	1.06
arachidonic acid monooxygenase activity	GO:0008391	7.03