| Disease ID | Disease name | Source of annotation with DDC | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| 608643 | AROMATIC L-AMINO ACID DECARBOXYLASE DEFICIENCY | OMIM, HUMSAVAR | link to OMIM | 1 | DDC |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| Metabolic pathways | hsa01100 | 2.49 |
| Cocaine addiction | hsa05030 | 7.07 |
| Amphetamine addiction | hsa05031 | 6.62 |
| Phenylalanine metabolism | hsa00360 | 8.6 |
| Alcoholism | hsa05034 | 5.59 |
| Serotonergic synapse | hsa04726 | 5.84 |
| Dopaminergic synapse | hsa04728 | 5.69 |
| Tryptophan metabolism | hsa00380 | 7.34 |
| Tyrosine metabolism | hsa00350 | 7.64 |
| Histidine metabolism | hsa00340 | 8.24 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Metabolism of amino acids and derivatives | R-HSA-71291 | 5.4 |
| Amine-derived hormones | R-HSA-209776 | 8.98 |
| Catecholamine biosynthesis | R-HSA-209905 | 10.98 |
| Metabolism | R-HSA-1430728 | 2.34 |
| Serotonin and melatonin biosynthesis | R-HSA-209931 | 10.66 |
| GO term | GO ID | GO IC |
|---|---|---|
| anion binding | GO:0043168 | 4.17 |
| carboxylic acid binding | GO:0031406 | 4.64 |
| lyase activity | GO:0016829 | 4.53 |
| carbon-carbon lyase activity | GO:0016830 | 5.81 |
| aromatic-L-amino-acid decarboxylase activity | GO:0004058 | 9.74 |
| enzyme binding | GO:0019899 | 2.27 |
| ion binding | GO:0043167 | 1.36 |
| catalytic activity | GO:0003824 | 1.05 |
| carboxy-lyase activity | GO:0016831 | 6.15 |
| cofactor binding | GO:0048037 | 4.16 |
| binding | GO:0005488 | 0.18 |
| protein binding | GO:0005515 | 0.46 |
| L-dopa decarboxylase activity | GO:0036468 | 9.74 |
| amino acid binding | GO:0016597 | 5.71 |
| protein domain specific binding | GO:0019904 | 3.32 |
| pyridoxal phosphate binding | GO:0030170 | 5.83 |