| Disease ID | Disease name | Source of annotation with DOCK2 | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| 616433 | IMMUNODEFICIENCY 40 | ClinVar, OMIM, HUMSAVAR | link to OMIM | 1 | DOCK2 |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| Chemokine signaling pathway | hsa04062 | 5.19 |
| Fc gamma R-mediated phagocytosis | hsa04666 | 6.21 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Infectious disease | R-HSA-5663205 | 4.47 |
| Host Interactions of HIV factors | R-HSA-162909 | 5.99 |
| HIV Infection | R-HSA-162906 | 5.22 |
| Nef and signal transduction | R-HSA-164944 | 9.98 |
| The role of Nef in HIV-1 replication and disease pathogenesis | R-HSA-164952 | 8.18 |
| Factors involved in megakaryocyte development and platelet production | R-HSA-983231 | 5.88 |
| Hemostasis | R-HSA-109582 | 3.98 |
| Disease | R-HSA-1643685 | 3.33 |
| GO term | GO ID | GO IC |
|---|---|---|
| Rac guanyl-nucleotide exchange factor activity | GO:0030676 | 7.17 |
| Ras guanyl-nucleotide exchange factor activity | GO:0005088 | 4.31 |
| GTPase activator activity | GO:0005096 | 4.11 |
| enzyme regulator activity | GO:0030234 | 2.85 |
| guanyl-nucleotide exchange factor activity | GO:0005085 | 4.02 |
| receptor binding | GO:0005102 | 2.43 |
| GTPase regulator activity | GO:0030695 | 4.01 |
| macromolecular complex binding | GO:0044877 | 2.61 |
| binding | GO:0005488 | 0.18 |
| protein binding | GO:0005515 | 0.46 |
| protein complex binding | GO:0032403 | 3.09 |
| Rho guanyl-nucleotide exchange factor activity | GO:0005089 | 5.37 |
| molecular function regulator | GO:0098772 | 2.51 |
| nucleoside-triphosphatase regulator activity | GO:0060589 | 3.92 |
| T cell receptor binding | GO:0042608 | 7.95 |
| enzyme activator activity | GO:0008047 | 3.56 |