Gene table of DPYS : dihydropyrimidinase

Gene-disease associations table

Disease ID	Disease name	Source of annotation with DPYS	OMIM link	Number of associated genes	genes
222748	DIHYDROPYRIMIDINASE DEFICIENCY	ClinVar, OMIM, HUMSAVAR	link to OMIM	1	DPYS

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
Drug metabolism - other enzymes	hsa00983	7.21
Metabolic pathways	hsa01100	2.49
Pantothenate and CoA biosynthesis	hsa00770	8.68
Pyrimidine metabolism	hsa00240	6.01
beta-Alanine metabolism	hsa00410	7.72

Associated REACTOME pathways

Associated GO terms for Molecular function

GO term	GO ID	GO IC
phosphoprotein binding	GO:0051219	5.64
zinc ion binding	GO:0008270	2.66
amino acid binding	GO:0016597	5.71
heterocyclic compound binding	GO:1901363	1.06
anion binding	GO:0043168	4.17
cation binding	GO:0043169	1.4
transition metal ion binding	GO:0046914	2.48
dihydropyrimidinase activity	GO:0004157	9.05
ion binding	GO:0043167	1.36
pyrimidine nucleobase binding	GO:0002061	9.74
hydrolase activity	GO:0016787	1.9
small molecule binding	GO:0036094	1.89
catalytic activity	GO:0003824	1.05
metal ion binding	GO:0046872	1.41
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	GO:0016812	7.79
organic cyclic compound binding	GO:0097159	1.05
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	GO:0016810	4.76
carboxylic acid binding	GO:0031406	4.64
protein binding	GO:0005515	0.46
nucleobase binding	GO:0002054	8.35
thymine binding	GO:0002059	9.74
uracil binding	GO:0002058	9.74
binding	GO:0005488	0.18