Gene table of FTO : FTO, alpha-ketoglutarate dependent dioxygenase

Gene-disease associations table

Disease ID	Disease name	Source of annotation with FTO	OMIM link	Number of associated genes	genes
612460	BODY MASS INDEX QUANTITATIVE TRAIT LOCUS 14	OMIM	link to OMIM	1	FTO
612938	GROWTH RETARDATION, DEVELOPMENTAL DELAY, AND FACIAL DYSMORPHISM	ClinVar, OMIM, HUMSAVAR	link to OMIM	1	FTO

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

Associated REACTOME pathways

Associated GO terms for Molecular function

GO term	GO ID	GO IC
cation binding	GO:0043169	1.4
transition metal ion binding	GO:0046914	2.48
dioxygenase activity	GO:0051213	5.25
catalytic activity	GO:0003824	1.05
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors	GO:0016706	5.95
DNA-N1-methyladenine dioxygenase activity	GO:0043734	8.64
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	GO:0016705	4.65
DNA demethylase activity	GO:0035514	8.64
oxidative RNA demethylase activity	GO:0035515	8.64
oxidative DNA demethylase activity	GO:0035516	9.74
ion binding	GO:0043167	1.36
ferrous iron binding	GO:0008198	6.65
demethylase activity	GO:0032451	6.21
RNA N6-methyladenosine dioxygenase activity	GO:1990931	9.74
binding	GO:0005488	0.18
iron ion binding	GO:0005506	4.65
metal ion binding	GO:0046872	1.41
oxidoreductase activity	GO:0016491	3.12