Disease ID | Disease name | Source of annotation with GPX4 | OMIM link | Number of associated genes | genes |
---|---|---|---|---|---|
250220 | SPONDYLOMETAPHYSEAL DYSPLASIA, SEDAGHATIAN TYPE | ClinVar, OMIM | link to OMIM | 1 | GPX4 |
Download the gene annotation in CSV format
KEGG pathway | KEGG ID | KEGG IC |
---|---|---|
Glutathione metabolism | hsa00480 | 6.96 |
REACTOME pathway | REACTOME ID | REACTOME IC |
---|---|---|
Synthesis of 12-eicosatetraenoic acid derivatives | R-HSA-2142712 | 10.4 |
Metabolism | R-HSA-1430728 | 2.34 |
Synthesis of 5-eicosatetraenoic acids | R-HSA-2142688 | 10.4 |
Arachidonic acid metabolism | R-HSA-2142753 | 7.34 |
Metabolism of lipids and lipoproteins | R-HSA-556833 | 3.79 |
Synthesis of 15-eicosatetraenoic acid derivatives | R-HSA-2142770 | 10.4 |
GO term | GO ID | GO IC |
---|---|---|
phospholipid-hydroperoxide glutathione peroxidase activity | GO:0047066 | 9.74 |
antioxidant activity | GO:0016209 | 5.49 |
catalytic activity | GO:0003824 | 1.05 |
oxidoreductase activity, acting on peroxide as acceptor | GO:0016684 | 6.0 |
peroxidase activity | GO:0004601 | 6.05 |
glutathione peroxidase activity | GO:0004602 | 6.85 |
oxidoreductase activity | GO:0016491 | 3.12 |